Zupanc Aleksander, Vidmar Gaj, Majdič Neža, Novak Primož
University Rehabilitation Institute.
Faculty of Medicine, University of Ljubljana, Ljubljana.
Int J Rehabil Res. 2023 Mar 1;46(1):53-60. doi: 10.1097/MRR.0000000000000558. Epub 2022 Dec 26.
Our aim was to evaluate health-related quality-of-life (HRQoL) of the patients with critical illness neuropathy and/or myopathy after severe COVID-19 during their rehabilitation. The prospective cohort study included 157 patients (median age 64 years) admitted to rehabilitation. HRQoL was assessed the using European Quality 5-Dimensions questionnaire [EQ-5D index , range 0(or exceptionally less) to 1, and Visual Analogue Scale (VAS), range 0-100], which was completed by the patients at admission and discharge. Additionally, they were assessed with the de Morton Mobility Index (DEMMI), the 6-Minute Walk Test (6MWT), and the Functional Independence Measure (FIM). Median EQ-5D index was 0.32 and median EQ VAS was 48 at admission, and median EQ-5D index was 0.61 and median EQ VAS 80 at discharge. Some or extreme problems were reported by 154 (98%) patients regarding the mobility dimension, 151 (96%) regarding usual activities, 136 (87%) regarding self-care, 84 (54%) regarding pain or discomfort dimension, and 52 patients (34%) regarding anxiety or depression at admission. At discharge, some or extreme problems were still reported by 96 patients (61%) regarding mobility, 95 (61%) regarding usual activities, 70 patients (45%) regarding pain or discomfort, 46 (29%) regarding self-care, and 19 patients (12%) regarding anxiety or depression. At the same time, the patients exhibited significant improvements in the DEMMI (median increased from 41 to 67 points), 6MWT (from 60 to 293 m) and motor FIM (from 56 to 84 points). The improvement of the self-reported HRQoL was, thus, paralleled by the improvements in clinician-assessed mobility, walking endurance and functional independence.
我们的目的是评估重症新型冠状病毒肺炎（COVID-19）后患有危重病性神经病和/或肌病的患者在康复期间的健康相关生活质量（HRQoL）。这项前瞻性队列研究纳入了157名接受康复治疗的患者（中位年龄64岁）。使用欧洲五维健康量表问卷[EQ-5D指数，范围为0（或极低）至1，以及视觉模拟量表（VAS），范围为0-100]对HRQoL进行评估，患者在入院时和出院时完成该问卷。此外，还使用德莫顿运动指数（DEMMI）、6分钟步行试验（6MWT）和功能独立性测量（FIM）对他们进行评估。入院时EQ-5D指数中位数为0.32，EQ VAS中位数为48；出院时EQ-5D指数中位数为0.61，EQ VAS中位数为80。入院时，154名（98%）患者报告在行动能力维度存在一些或极端问题，151名（96%）患者在日常活动方面存在问题，136名（87%）患者在自我护理方面存在问题，84名（54%）患者在疼痛或不适维度存在问题，52名（34%）患者在焦虑或抑郁方面存在问题。出院时，96名（61%）患者仍报告在行动能力方面存在一些或极端问题，95名（61%）患者在日常活动方面存在问题，70名（45%）患者在疼痛或不适方面存在问题，46名（29%）患者在自我护理方面存在问题，19名（12%）患者在焦虑或抑郁方面存在问题。同时，患者在DEMMI（中位数从41分提高到67分）、6MWT（从60米提高到293米）和运动FIM（从56分提高到84分）方面有显著改善。因此，自我报告的HRQoL的改善与临床医生评估的行动能力、步行耐力和功能独立性的改善是并行的。
