Department of Medicine, Dhaka Medical College, Dhaka, Bangladesh.
Department of Neurology, Dhaka Medical College, Dhaka, Bangladesh.
PLoS One. 2023 Jan 31;18(1):e0280882. doi: 10.1371/journal.pone.0280882. eCollection 2023.
There is increasing evidence of the post-COVID-19 suffering and decreased quality of life in the COVID-19 patients. This study aimed to assess the quality of life and associated factors of COVID-19 patients at one month after discharge from the hospital. This was a cross-sectional study that was conducted at the post-covid clinic of Dhaka Medical College Hospital (DMCH) where RT-PCR-confirmed adult COVID-19 recovered patients were enrolled one month after discharge from the same hospital. They were consecutively selected from January 01 to May 30. A pretested semi-structured questionnaire was used for the data collection for clinical variables. The generic multi-attributable utility instrument EQ-5D-5L was used for assessing health-related quality of life (HRQoL). A total of 563 patients were enrolled in the study. The patients had a mean age with standard deviation (±SD) of 51.18 (±13.49) years and 55.95% were male. The mean (SD) EQ-5D-5L index score and EQ-VAS scores were 0.78 (±0.19) and 70.26 (±11.13), respectively. Overall, 45.77%, 50.99%, 52.79%, 55.14% and 62.16% had problems (slight to extreme) in the mobility, self-care, usual activities, pain/discomfort and anxiety/depression dimensions, respectively. Patients aged ≥60 years had significant problem in mobility (odds ratio [OR] 3.24, 95% confidence interval [CI]: 1.07-9.77). Female participants were 5.50 times (95% CI: 2.22-13.62) more likely to have problems in their usual activities. In comparison to urban area, living in a peri-urban setting was significantly associated with problems in mobility (OR 1.89, 95% CI: 1.13-3.20), pain/discomfort (OR 1.82, 95% CI: 1.04-3.12) and anxiety/depression (OR 2.16, 95% CI: 1.22-3.84). Comorbid patients were 1.75 times (95% CI: 1.07-2.85) more likely to report problems in the pain/discomfort dimension. Presence of symptom(s) was associated with problems in self-care (OR 3.27, 95%CI: 1.31-8.18), usual-activity (OR 3.08, 95%CI: 1.21-7.87), pain/discomfort dimensions (OR 2.75, 95%CI: 1.09-6.96) and anxiety/depression (OR 3.35, 95%CI: 1.35-8.30). Specific management strategies should be planned to address the factors associated with low health-related quality of life in post-acute care of COVID-19 patients.
越来越多的证据表明，COVID-19 患者在 COVID-19 后会遭受痛苦，生活质量下降。本研究旨在评估 COVID-19 患者出院后一个月的生活质量及其相关因素。这是一项横断面研究，在达卡医学院医院（DMCH）的新冠后诊所进行，在该诊所招募了从同一医院出院后一个月的经 RT-PCR 确诊的成年 COVID-19 康复患者。他们是从 2023 年 1 月 1 日至 5 月 30 日连续入选的。使用经过预测试的半结构式问卷收集临床变量数据。使用通用多归因效用仪器 EQ-5D-5L 评估健康相关生活质量（HRQoL）。共有 563 名患者入组本研究。患者的平均年龄为 51.18±13.49 岁，55.95%为男性。平均（SD）EQ-5D-5L 指数评分和 EQ-VAS 评分分别为 0.78（±0.19）和 70.26（±11.13）。总体而言，45.77%、50.99%、52.79%、55.14%和 62.16%在移动性、自我护理、日常活动、疼痛/不适和焦虑/抑郁维度上存在轻微到严重的问题。60 岁及以上的患者在移动性方面存在显著问题（比值比 [OR] 3.24，95%置信区间 [CI]：1.07-9.77）。女性参与者在日常活动方面出现问题的可能性是男性的 5.50 倍（95% CI：2.22-13.62）。与城市地区相比，居住在城乡结合部与移动性（OR 1.89，95% CI：1.13-3.20）、疼痛/不适（OR 1.82，95% CI：1.04-3.12）和焦虑/抑郁（OR 2.16，95% CI：1.22-3.84）方面出现问题显著相关。合并症患者在疼痛/不适维度上出现问题的可能性是无合并症患者的 1.75 倍（95% CI：1.07-2.85）。存在症状与自我护理（OR 3.27，95%CI：1.31-8.18）、日常活动（OR 3.08，95%CI：1.21-7.87）、疼痛/不适维度（OR 2.75，95%CI：1.09-6.96）和焦虑/抑郁（OR 3.35，95%CI：1.35-8.30）出现问题相关。应制定特定的管理策略，以解决 COVID-19 患者急性后期与生活质量相关的因素。
