Faculty of Medicine, Department of Internal Medicine, Universitas Sumatera Utara, Medan, Indonesia.
Faculty of Medicine, Andrology Study Program, Universitas Airlangga, Surabaya, Indonesia.
PLoS One. 2023 Feb 2;18(2):e0280915. doi: 10.1371/journal.pone.0280915. eCollection 2023.
The purpose of this study was to examine the sex lives of male cirrhotic patients organic factors affect them.
We did an observational study of 220 cirrhotic men's satisfaction with their sexual lives. Assessment of sex satisfaction was carried out using the New Sexual Satisfaction Scale. The frequency of intercourse and masturbation was estimated. Then, the levels of albumin, total bilirubin, vitamin D, and sex steroids were examined. Ascites and sarcopenia subgroups of our patients were stratified.
Along with sex steroids, albumin, total bilirubin, and vitamin D all had an impact on how satisfying sex was (r = 0.22), (r = 0.24), and (r = -0.17) affected sex satisfaction. There were strong positive correlations between vitamin D (r = 0.33), albumin (r = 0.59), and free testosterone, along with a negative correlation between total bilirubin (r = -0.63) and free testosterone. An imbalance in sex steroid levels was observed, leading to decreased frequency of intercourse(p < 0.0001), weakened erections(p < 0.0001), and reduced quality of orgasm (p < 0.0001). Significant new sex behavior changes were found, such as an increase in masturbation. Physical limitations such as ascites and sarcopenia also impacted the decreasing sex life.
The sex life of cirrhotic men is affected. The decrease in the frequency of intercourse and sexual satisfaction is noticeable in male patients and leads to increased masturbation. Free Testosterone, vitamin D, albumin, and bilirubin play role in their sex life. In addition, ascites and sarcopenia not only affect their sex life but also hamper the quality of their well-being.
本研究旨在探讨男性肝硬化患者的性生活，研究有机因素对他们的影响。
我们对 220 名肝硬化男性患者的性生活满意度进行了观察性研究。使用新性满意度量表评估性满意度。估计性交和手淫的频率。然后检查白蛋白、总胆红素、维生素 D 和性激素的水平。对我们患者的腹水和肌肉减少症亚组进行分层。
除了性激素外，白蛋白、总胆红素和维生素 D 都会影响性满意度（r = 0.22）、（r = 0.24）和（r = -0.17）。维生素 D（r = 0.33）、白蛋白（r = 0.59）和游离睾酮之间存在强烈的正相关，而总胆红素（r = -0.63）与游离睾酮之间存在负相关。观察到性激素水平失衡，导致性交频率降低（p < 0.0001）、勃起减弱（p < 0.0001）和性高潮质量下降（p < 0.0001）。发现了显著的新性行为变化，例如手淫增加。腹水和肌肉减少症等身体限制也会影响性生活质量下降。
肝硬化男性的性生活受到影响。男性患者的性交频率和性满意度明显下降，导致手淫增加。游离睾酮、维生素 D、白蛋白和胆红素在他们的性生活中发挥作用。此外，腹水和肌肉减少症不仅影响他们的性生活，还会影响他们的整体幸福感。
