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[慢性肾衰竭癌症患者的最佳疼痛管理]

[Optimal pain management for cancer patients with chronic renal failure].

作者信息

Fulcrand Julie, Delvoye-Heiremans Julie, Lemaire Antoine

机构信息

UF pharmacie clinique, pôle cancérologie & spécialités médicales, centre hospitalier de Valenciennes, Valenciennes, France.

Département interdisciplinaire de soins de support pour le patient oncologique, pôle cancérologie & spécialités médicales, centre hospitalier de Valenciennes, Valenciennes, France.

出版信息

Bull Cancer. 2024 Jul-Aug;111(7-8):754-764. doi: 10.1016/j.bulcan.2022.12.008. Epub 2023 Jan 31.

DOI:10.1016/j.bulcan.2022.12.008
PMID:36732141
Abstract

The management of multimorphic cancer pain is a major supportive care in oncology, for which many national and international recommendations have recently been updated. Any cancer patient must benefit from access to supportive care from the diagnosis, throughout the entire care pathway. Chronic renal failure, from any etiology, requires special attention and constant attention to details from interdisciplinary caregivers' teams to propose the best analgesic therapeutic strategy, combining complementary and interventional approaches to treatments. Analgesic therapies, in particular opioids and antineuropathics, require specific precautions. A therapeutic alliance integrating clinical pharmacy as a supportive care in its own right, is a major asset allowing the optimization and securing of analgesic drug treatments, conditioning both their efficacy, their tolerance and therapeutic observance, in the goal of improving the patient's quality of life.

摘要

多形性癌痛的管理是肿瘤学中的一项重要支持性护理,许多国家和国际指南最近都对此进行了更新。任何癌症患者都应从诊断开始,在整个治疗过程中受益于支持性护理。任何病因引起的慢性肾衰竭都需要特别关注,跨学科护理团队要始终注重细节,以提出最佳的镇痛治疗策略,将补充性和介入性治疗方法相结合。镇痛治疗,尤其是阿片类药物和抗神经病药物,需要采取特定的预防措施。将临床药学本身作为一种支持性护理纳入治疗联盟,是一项重要资产,有助于优化和确保镇痛药物治疗,决定其疗效、耐受性和治疗依从性,以提高患者的生活质量。

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