From the Department of Orthopaedics and Rehabilitation, Yale School of Medicine, New Haven, CT.
J Am Acad Orthop Surg Glob Res Rev. 2022 Dec 5;6(12). doi: 10.5435/JAAOSGlobal-D-22-00040. eCollection 2022 Dec 1.
The association of preoperative narcotic use with postoperative outcomes after primary elective total knee arthroplasty (TKA) has remained poorly characterized. The NarxCare platform analyzes patients' state Prescription Drug Monitoring Program records to assign numerical scores that approximate a patient's overall opioid usage. The present study investigated the utility of admission NarxCare narcotic scores in predicting the odds of adverse events (AEs) after primary elective TKA.
Elective primary TKA patients performed at a single institution between October 2017 and May 2020 were evaluated. NarxCare narcotic scores at the time of admission, patient characteristics, 30-day AEs, readmissions, revision surgeries, and mortality were abstracted. Elective TKA patients were binned based on admission NarxCare narcotic scores. The odds of experiencing adverse outcomes were compared.
In total, 1136 patients met the criteria for inclusion in the study (Narx Score 0: n = 293 [25.8%], 1 to 99: n = 253 [22.3%], 100 to 299: n = 368 [32.4%], 300 to 499: n = 161 [14.2%], and 500+: n = 61 [5.37%]). By logistic regression, patients with higher admission narcotic scores tended to have a dose-dependent increase in the odds of prolonged length of hospital stay, readmission within 30 days, and aggregated AEs.
Admission narcotic scores may be used to predict readmission and to stratify TKA patients by risk of AEs.
术前使用麻醉药物与初次择期全膝关节置换术(TKA)后的术后结果之间的关联仍未得到充分描述。NarxCare 平台分析患者的州处方药物监测计划记录,以分配近似患者总体阿片类药物使用量的数值评分。本研究调查了入院时 NarxCare 麻醉评分在预测初次择期 TKA 后不良事件(AE)发生几率方面的效用。
评估了 2017 年 10 月至 2020 年 5 月在一家机构进行的初次择期 TKA 患者。提取入院时的 NarxCare 麻醉评分、患者特征、30 天 AE、再入院、翻修手术和死亡率等数据。根据入院时的 NarxCare 麻醉评分将初次择期 TKA 患者分为不同的组。比较各组发生不良结局的几率。
共有 1136 名患者符合纳入本研究的标准(Narx 评分 0:n = 293 [25.8%],1 至 99:n = 253 [22.3%],100 至 299:n = 368 [32.4%],300 至 499:n = 161 [14.2%],500 及以上:n = 61 [5.37%])。通过逻辑回归,入院时麻醉评分较高的患者,其住院时间延长、30 天内再入院和总 AE 的几率呈剂量依赖性增加。
入院麻醉评分可用于预测再入院,并对 TKA 患者进行 AE 风险分层。