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[1例腹腔镜腹会阴联合切除术及会阴重建治疗源于肛门腺的伴皮肤浸润的印戒细胞癌]

[A Case of Laparoscopic Abdominoperineal Resection and Perineal Reconstruction for Signet-Ring Cell Carcinoma with Skin Invasion Derived from the Anal Gland].

作者信息

Nakamura Kaori, Ono Tomoyuki, Kobayashi Minoru, Kajiwara Taiki, Karasawa Hideaki, Kohyama Atsushi, Watanabe Kazuhiro, Kamei Takashi, Ohnuma Shinobu, Unno Michiaki

机构信息

Dept. of Surgery, Tohoku University Graduate School of Medicine.

出版信息

Gan To Kagaku Ryoho. 2022 Dec;49(13):1876-1878.

Abstract

A 56-year-old man was referred to our hospital with an awareness of anal tumor. The tumor extended from the anal verge to the back of left testicle. Colonoscopy showed no tumor in the rectum and the anal canal. Biopsy showed mucus- producing adenocarcinoma(sig), and we diagnosed anal canal adenocarcinoma with immunostaining. Laparoscopic abdominoperineal rectal resection and perineal reconstruction with the V-Y fasciocutaneous flap closure technique. The patient had no major postoperative complications, and was discharged on 23rd postoperative day. Pathological examination revealed that the tumor was pT3N0M0, pStage ⅡB. The patient received adjuvant chemotherapy with CAPOX and has survived 12 months without recurrence. Immunostaining may be used to diagnose the signet-ring cell carcinoma without tumor of anal canal. In addition, reconstruction of the perineum for large anal tumors is useful.

摘要

一名56岁男性因察觉到肛门肿瘤而被转诊至我院。肿瘤从肛门边缘延伸至左侧睾丸后方。结肠镜检查显示直肠和肛管未发现肿瘤。活检显示为黏液腺癌(印戒细胞型),通过免疫染色我们诊断为肛管腺癌。采用腹腔镜腹会阴直肠切除术及V-Y筋膜皮瓣闭合技术进行会阴重建。患者术后无重大并发症,术后第23天出院。病理检查显示肿瘤为pT3N0M0,pⅡB期。患者接受了CAPOX辅助化疗,已存活12个月且无复发。免疫染色可用于诊断无肛管肿瘤的印戒细胞癌。此外,对于较大的肛门肿瘤,会阴重建是有效的。

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