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[精神科实践中老年痴呆症和阿尔茨海默病的诊断不足与过度诊断]

[Hypo- and hyperdiagnosis of senile dementia and Alzheimer's disease in psychiatric practice].

作者信息

Shefer V F

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1987;87(7):987-92.

PMID:3673398
Abstract

A total of 714 brains from patients of predominantly advanced age who died in mental (n = 546) and somatic (n = 168) institutions have been examined macro- and microscopically. It has been found on the basis of accurate postmortem verification of Alzheimer's disease (AD) and senile dementia (SD) that in 20% of cases psychiatrists erroneously diagnose feeblemindedness in old age and in about the same proportion of cases they fail to diagnose the actual disease (most often AD and SD). The author has revealed a marked hyperdiagnosis of hypophrenias of vascular genesis at the expense of AD and SD whose rates are obviously underreported and which play a greater role in gerontopsychiatric practice than is generally accepted.

摘要

对来自主要为老年患者的714个大脑进行了大体和显微镜检查,这些患者死于精神病院(n = 546)和躯体病院(n = 168)。基于对阿尔茨海默病(AD)和老年痴呆症(SD)的准确尸检验证发现,在20%的病例中,精神科医生错误地将老年痴呆诊断为智力低下,并且在大约相同比例的病例中,他们未能诊断出实际疾病(最常见的是AD和SD)。作者发现,以AD和SD为代价,血管性痴呆的过度诊断明显,而AD和SD的发病率明显被低估,并且在老年精神病学实践中比普遍认为的发挥着更大的作用。

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[Hypo- and hyperdiagnosis of senile dementia and Alzheimer's disease in psychiatric practice].[精神科实践中老年痴呆症和阿尔茨海默病的诊断不足与过度诊断]
Zh Nevropatol Psikhiatr Im S S Korsakova. 1987;87(7):987-92.
2
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引用本文的文献

1
Cross-national comparisons of the occurrence of Alzheimer's and vascular dementias.阿尔茨海默病和血管性痴呆症发病率的跨国比较。
Eur Arch Psychiatry Clin Neurosci. 1991;240(4-5):218-22. doi: 10.1007/BF02189530.