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三级医院在新冠疫情期间对结核病诊断的影响

Impact on tuberculosis diagnostic during COVID-19 pandemic in a tertiary care hospital.

作者信息

Ruiz-Bastián Mario, Díaz-Pollán Beatriz, Falces-Romero Iker, Toro-Rueda Carlos, García-Rodríguez Julio

机构信息

Clinical Microbiology and Parasitology Department, Hospital Universitario La Paz, Madrid, Spain.

Infectious Disease Unit, Hospital Universitario La Paz, Madrid, Spain; IdiPAZ (La Paz Institute for Health Research), La Paz University Hospital, Madrid, Spain; CIBERINFEC (Centre for Biomedical Research Network on Infectious Diseases), Instituto de Salud Carlos III, Madrid, Spain.

出版信息

Enferm Infecc Microbiol Clin (Engl Ed). 2024 Mar;42(3):135-139. doi: 10.1016/j.eimce.2022.11.020. Epub 2023 Feb 1.

Abstract

INTRODUCTION

The aim of this study is to review how did the first three COVID-19 waves affected the diagnostic of tuberculosis and to describe the extra-pulmonary Mycobacterium tuberculosis complex (TB) diagnosis.

MATERIALS AND METHODS

A retrospective observational study was done during the first three waves of pandemic to ascertain the impact on TB samples and to recover the extra-pulmonary TB cases we included the first two years of COVID-19. All relevant data was recovered from hospital and Clinical Microbiology records.

RESULTS

Prepandemic period showed an average of 44 samples per week for TB study; during the first three waves this number dropped to 23.1 per week. A reduction of 67.7% of pulmonary TB diagnosis was observed and an increase of 33.3% diagnosis of extra-pulmonary TB was noted when comparing pre-pandemic and pandemic period.

DISCUSSION

The number of declared cases and samples for TB diagnosis dropped during the first three COVID-19 waves due to the overstretched Public Health System which could lead to a delay in diagnosis, treatment and to the spread of TB disease in the general population. Surveillance programs should be reinforced to avoid this.

摘要

引言

本研究的目的是回顾新冠疫情前三波对结核病诊断的影响,并描述肺外结核分枝杆菌复合群(TB)的诊断情况。

材料与方法

在疫情的前三波期间进行了一项回顾性观察研究,以确定对结核病样本的影响,并找回肺外结核病例。我们纳入了新冠疫情的前两年。所有相关数据均从医院和临床微生物学记录中获取。

结果

疫情前时期,每周平均有44份用于结核病研究的样本;在前三波疫情期间,这一数字降至每周23.1份。与疫情前和疫情期间相比,肺结核诊断减少了67.7%,肺外结核诊断增加了33.3%。

讨论

在新冠疫情的前三波期间,报告的结核病诊断病例和样本数量下降,原因是公共卫生系统不堪重负,这可能导致诊断、治疗延迟以及结核病在普通人群中的传播。应加强监测计划以避免这种情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/68ec/9890387/b083d467a11b/gr1_lrg.jpg

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