Albrijawy Reham, Alomar Khaled, Aldeen Rahaf Sharaf, Sharief Fawaz A L, Marwa Ghassan, Dalati Husam
Damascus University, Syria.
Damascus University, Syria; Pediatrics' University Hospital, Syria.
Int J Surg Case Rep. 2023 Feb;103:107914. doi: 10.1016/j.ijscr.2023.107914. Epub 2023 Feb 3.
Benign cystic teratoma considered an extragonadal germ cell tumor that can present at any age and mostly located in the anterior mediastinum, only 3 %-8 % are in the posterior mediastinum. Meningomyelocele is an abnormal herniation of the meninges that located in most cases posteriorly in lumbosacral spine. Cervicothoracic meningomyelocele are rare entities resemble only 1 %-5 % of all neural tube defects. The presence of both anterior meningomyelocele (MMC) an benign teratoma is very rare and this association in the thoracic column has never been mentioned before in the medical literature.
We present the case of a one-year-old child, who was admitted to our hospital with a complaint recurrent vomiting episode, and respiratory distress, with no improvement in symptoms after conservative treatment. Computed tomography showed an anterior heterogeneous meningomyelocele that extend posteriorly to the upper lobe of right lung tissue. MRI confirmed the presence of the meningomyelocele in addition to a heterogenous cystic structure within. Thoracotomy was indicated and the meningomyelocele was carefully resected and sent to histopathology analysis which showed the presence of a benign teratoma accompanying the meningomyelocele.
Meningomyeloceles and teratoma are rarely associated, especially in the thoracic spine. Mediastinal tumors should be taken into consideration when a mass is found. A thorough imaging investigations is crucial in establishing the diagnosis along with histopathology after complete resection.
In the presence of posterior mediastinal meningomyelocele with heterogeneity, a histopathological examination of the specimen should be performed to exclude the mediastinal tumors.
良性囊性畸胎瘤被认为是一种性腺外生殖细胞肿瘤,可在任何年龄出现,主要位于前纵隔,仅3%-8%位于后纵隔。脊髓脊膜膨出是指脑膜的异常疝出,大多数情况下位于腰骶部脊柱后方。颈胸段脊髓脊膜膨出是罕见的实体,仅占所有神经管缺陷的1%-5%。前脊髓脊膜膨出(MMC)和良性畸胎瘤同时存在的情况非常罕见,且医学文献中从未提及过胸椎部位的这种关联。
我们报告一例1岁儿童,因反复呕吐发作和呼吸窘迫入院,保守治疗后症状无改善。计算机断层扫描显示一个前部不均匀的脊髓脊膜膨出,向后延伸至右肺组织上叶。磁共振成像证实存在脊髓脊膜膨出,内部还有一个不均匀的囊性结构。遂行开胸手术,仔细切除脊髓脊膜膨出并送去做组织病理学分析,结果显示脊髓脊膜膨出伴有一个良性畸胎瘤。
脊髓脊膜膨出和畸胎瘤很少相关,尤其是在胸椎部位。发现肿块时应考虑纵隔肿瘤。全面的影像学检查对于明确诊断至关重要,完整切除后还需进行组织病理学检查。
对于存在异质性的后纵隔脊髓脊膜膨出,应进行标本的组织病理学检查以排除纵隔肿瘤。