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婴儿前纵隔成熟囊性畸胎瘤 4 个月:1 例罕见病例报告。

Mature cystic teratoma of anterior mediastinum in a 4-month-old infant: a rare case report.

机构信息

Department of Radiology and Radiotherapy, School of Medicine, Makerere University College of Health Sciences, P.O. Box 7072, Kampala, Uganda.

Department of Pediatrics and Child Health, School of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.

出版信息

Gen Thorac Cardiovasc Surg. 2021 Jun;69(6):1016-1021. doi: 10.1007/s11748-021-01590-9. Epub 2021 Jan 15.

DOI:10.1007/s11748-021-01590-9
PMID:33449267
Abstract

Teratomas of anterior mediastinum are rare tumors and are often slow growing, asymptomatic and detected incidentally on chest imaging. We report, a rare case of an anterior mediastinal teratoma occurring in early childhood. A 4-month-old male infant presented to the pediatric unit of our hospital with a 2-week history of a progressive difficulty in breathing and stridor. He had received several courses of oral and intravenous antibiotics for a clinical diagnosis of pneumonia. The baby started to show social smile and hold his head fairly steady. Chest radiography and chest ultrasound revealed a cystic anterior mediastinal mass which was confirmed by a contrasted chest CT. An ultrasound-guided trucut biopsy of the mass was performed and histopathology showed mature cystic teratoma. Surgical removal of the mass was done with excellent post-operative outcome. Occurrence of a mature cystic anterior mediastinal teratoma is uncommon in early infancy. Early and complete surgical resection offers the best possible prognosis.

摘要

前纵隔畸胎瘤较为罕见,生长缓慢,多无症状,常在胸部影像学检查时偶然发现。我们报告了 1 例发生于婴幼儿期的前纵隔畸胎瘤罕见病例。1 名 4 月龄男婴因呼吸困难和喘鸣进行性加重 2 周,至我院儿科就诊。患儿曾接受数轮口服和静脉用抗生素治疗,临床诊断为肺炎。患儿开始出现社交微笑,能较为稳定地抬头。胸部 X 线和胸部超声检查提示前纵隔囊性肿块,胸部 CT 增强扫描进一步证实了这一发现。对肿块行超声引导下穿刺活检,组织病理学检查提示成熟囊性畸胎瘤。肿块完全切除术后患儿恢复良好。在婴儿早期,成熟囊性前纵隔畸胎瘤较为罕见。早期、完全的手术切除可获得最佳预后。

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本文引用的文献

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Primary germ cell tumor of the mediastinum - presenting as a huge mass.纵隔原发性生殖细胞肿瘤——表现为巨大肿块。
Int J Prev Med. 2014 Feb;5(2):230-2.
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Synthesis of -fetoprotein by liver, yolk sac, and gastrointestinal tract of the human conceptus.人类胚胎的肝脏、卵黄囊和胃肠道中甲胎蛋白的合成。
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