Alizarin: Prospects and sustainability for food safety and quality monitoring applications.

Active and intelligent food packaging has emerged to ensure food safety, quality, or spoilage monitoring and extend the shelf life of food. The development of intelligent packaging has accelerated significantly in recent years with a focus on monitoring changes in the quality of packaged products in real-time throughout the food supply chain. As one of the popular natural colorants, alizarin has attracted much consideration due to its excellent functional properties and quality to color change under varying pH. Alizarin is an efficient and cost-effective biomaterial with numerous biological features such as antioxidant, antibacterial, non-cytotoxic, and antitumor. This review focuses on an in-depth summary and prospects for alizarin as a natural and safe colorant that has the potential to be incorporated into intelligent packaging to track the freshness of packaged foodstuffs. The use of alizarin as an intelligent packaging agent shows huge potential for the application of food packaging and brings it one step closer to real-time monitoring of food quality throughout the supply chain. Finally, various limitations and future requirements are discussed to underscore the importance of developing alizarin-based intelligent functional food packaging systems.