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口服葡萄糖耐量试验和连续血糖监测在妊娠期糖尿病诊断中的应用:一项针对女性和医护专业人员的调查研究。

Oral glucose tolerance test and continuous glucose monitoring for gestational diabetes diagnosis: a survey study of women and health care professionals.

机构信息

School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia.

Diabetes Clinic, Royal Hospital for Women, Sydney, NSW, Australia.

出版信息

Arch Gynecol Obstet. 2024 Feb;309(2):483-489. doi: 10.1007/s00404-023-06949-2. Epub 2023 Feb 5.

Abstract

AIMS

The oral glucose tolerance test (OGTT), used for gestational diabetes mellitus (GDM) diagnosis for over 65 years, has poor acceptability and tolerability. Continuous glucose monitoring is being considered as potential alternative. The aim of our study was to formally assess women's and health care professionals' perception of both tests as diagnostic tools for GDM.

METHODS

Participants in a pilot study on continuous glucose monitoring for GDM diagnosis were invited to fill two questionnaires, each of 6 Likert-scale and one optional open-ended question. A range of healthcare practitioners were also invited to fill a questionnaire of 13 Likert-scale and 7 optional open-ended questions.

RESULTS

Sixty women completed the OGTT and 70 the continuous glucose monitoring questionnaire. OGTT was reported as poorly acceptable. Continuous glucose monitoring was described as significantly more tolerable (81% vs 27% 5/5 general acceptability rate, p < 0.001); ninety-three percent of the participants would recommend it for GDM diagnosis. Thirty health care professionals completed the survey. Most of them (73%) had confidence in OGTT as a diagnostic test for GDM with 66% raising some concerns. Doubts on continuous glucose monitoring were raised in terms of costs, accessibility and accuracy for GDM diagnosis due to "lack of evidence".

CONCLUSIONS

Continuous glucose monitoring was substantially better tolerated for women than OGTT. Current lack of evidence for diagnostic accuracy for GDM underlines the need for studies on correlation between continuous glucose monitoring parameters and pregnancy outcomes to strengthen evidence for its use as diagnostic test for GDM.

摘要

目的

口服葡萄糖耐量试验(OGTT)用于诊断妊娠糖尿病(GDM)已有 65 年以上,但其接受度和耐受性均较差。连续血糖监测正被视为一种潜在的替代方法。本研究旨在正式评估女性和医疗保健专业人员对这两种检测方法作为 GDM 诊断工具的看法。

方法

我们邀请了一项关于连续血糖监测用于 GDM 诊断的试点研究的参与者填写两份问卷,每份问卷均有 6 个 Likert 量表和一个可选的开放式问题。我们还邀请了一系列医疗保健从业者填写一份包含 13 个 Likert 量表和 7 个可选开放式问题的问卷。

结果

共有 60 名女性完成了 OGTT 检查,70 名女性完成了连续血糖监测问卷。OGTT 的接受度较差。连续血糖监测的耐受性明显更好(81%比 27%,5/5 的总体接受率,p<0.001);93%的参与者会推荐其用于 GDM 诊断。30 名医疗保健专业人员完成了调查。他们中的大多数(73%)对 OGTT 作为 GDM 诊断的检测方法有信心,但有 66%的人提出了一些担忧。由于“缺乏证据”,连续血糖监测在成本、可及性和 GDM 诊断准确性方面存在疑虑。

结论

与 OGTT 相比,连续血糖监测在女性中更能被耐受。目前缺乏关于其在 GDM 诊断准确性方面的证据,这凸显了开展关于连续血糖监测参数与妊娠结局之间相关性的研究的必要性,以加强其作为 GDM 诊断检测方法的证据。

相似文献

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Continuous Glucose Monitoring in Women with Normal OGTT in Pregnancy.妊娠期正常 OGTT 妇女的连续血糖监测。
J Diabetes Res. 2021 Aug 23;2021:9987646. doi: 10.1155/2021/9987646. eCollection 2021.

本文引用的文献

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The role of continuous glucose monitoring in pregnancy.持续血糖监测在孕期的作用。
Obstet Med. 2022 Mar;15(1):6-10. doi: 10.1177/1753495X211014716. Epub 2021 May 27.

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