口服葡萄糖耐量试验——是时候做出改变了吗？——一篇以妊娠为重点的文献综述
The Oral Glucose Tolerance Test-Is It Time for a Change?-A Literature Review with an Emphasis on Pregnancy.
作者信息
Bogdanet Delia, O'Shea Paula, Lyons Claire, Shafat Amir, Dunne Fidelma
机构信息
Department of Medicine, School of Medicine, National University of Ireland Galway, H91TK33 Galway, Ireland.
Department of Diabetes and Endocrinology, Saolta University Health Care Group (SUHCG), University Hospital Galway, H91YR71 Galway, Ireland.
出版信息
J Clin Med. 2020 Oct 27;9(11):3451. doi: 10.3390/jcm9113451.
Globally, gestational diabetes (GDM) is increasing at an alarming rate. This increase is linked to the rise in obesity rates among women of reproductive age. GDM poses a major global health problem due to the related micro- and macro-vascular complications of subsequent Type 2 diabetes and the impact on the future health of generations through the long-term impact of GDM on both mothers and their infants. Therefore, correctly identifying subjects as having GDM is of utmost importance. The oral glucose tolerance test (OGTT) has been the mainstay for diagnosing gestational diabetes for decades. However, this test is deeply flawed. In this review, we explore a history of the OGTT, its reproducibility and the many factors that can impact its results with an emphasis on pregnancy.
在全球范围内，妊娠期糖尿病（GDM）的发病率正以惊人的速度上升。这种增长与育龄女性肥胖率的上升有关。由于后续2型糖尿病相关的微血管和大血管并发症，以及GDM对母亲及其婴儿的长期影响对后代未来健康产生的影响，GDM构成了一个重大的全球健康问题。因此，正确识别患有GDM的受试者至关重要。几十年来，口服葡萄糖耐量试验（OGTT）一直是诊断妊娠期糖尿病的主要方法。然而，这项测试存在严重缺陷。在本综述中，我们探讨了OGTT的历史、其可重复性以及许多可能影响其结果的因素，重点是妊娠。
Zotero 插件