Dutt Aishwarya Sunil, Bakhshi Girish, Sabale Chandrakant, Landge Ravi, Baligar Sushrut, V Rajalakshmi, Jha Madhu, Joshi Sampada, Teja Chettubattina Ravi
Department of General Surgery, Grant Government Medical College and Sir J. J. Group of Hospitals, Mumbai, Maharashtra, India.
Surg J (N Y). 2023 Feb 3;9(1):e23-e27. doi: 10.1055/s-0042-1758668. eCollection 2023 Jan.
Phyllodes is a rare tumor found exclusively in females. It can be classified into benign, intermediate, or malignant variety based on the aggressive nature of the disease. With adequate preoperative clinical assessment combined with histopathology and radiological investigations the adequate treatment strategy can be formulated to avoid future recurrences. Complete androgen insensitivity syndrome (CAIS) is associated with a genotypic male, which can be confirmed by karyotyping, with phenotypic female characteristics. The present case is the first case of bilateral breast phyllodes tumor in a patient with CAIS. Preoperative assessment was suggestive of bilateral phyllodes tumor with bilateral gonads in the inguinal region which was confirmed to be testis postoperatively on histopathological analysis. A brief case report with review of literature is presented.
叶状肿瘤是一种仅在女性中发现的罕见肿瘤。根据疾病的侵袭性，它可分为良性、中间型或恶性类型。通过充分的术前临床评估，结合组织病理学和影像学检查，可以制定适当的治疗策略以避免未来复发。完全性雄激素不敏感综合征（CAIS）与基因型男性相关，可通过核型分析确诊，具有表型女性特征。本病例是首例患有CAIS的双侧乳腺叶状肿瘤患者。术前评估提示双侧叶状肿瘤伴双侧性腺位于腹股沟区，术后组织病理学分析证实为睾丸。本文呈现了一份简短的病例报告并对文献进行了综述。
