Yoon Seo Yeon
Department of Physical Medicine and Rehabilitation, Korea University Guro Hospital, Seoul, Korea.
Brain Neurorehabil. 2022 Jul 26;15(2):e15. doi: 10.12786/bn.2022.15.e15. eCollection 2022 Jul.
Parkinson's disease (PD) is the second most common neurodegenerative disorder. Although dopaminergic drugs are the mainstay for improving PD symptoms, there are still few effective disease-modifying therapies. With the increasing prevalence of PD and the rapid transition to an aging society, more emphasis needs to be placed on rehabilitation that could slow the disease progression combined with pharmacological therapy. In this review, we present an update on evidence related to rehabilitation programs for motor function, swallowing difficulty, and speech disorders in PD. Aerobic exercise, music therapy, dance, virtual reality, and non-invasive brain stimulation have been shown to improve motor function, and telerehabilitation could also be feasibly applied in PD. Recent studies have shown the effectiveness of expiratory muscle strengthening exercises and Lee Silverman Voice Treatment for swallowing difficulty and speech disorders, respectively. Although many rehabilitation programs have been tried, the evidence is still limited. Well-designed future randomized controlled trials with large numbers of participants are needed to establish evidence for rehabilitation in PD.
帕金森病(PD)是第二常见的神经退行性疾病。尽管多巴胺能药物是改善PD症状的主要手段,但仍缺乏有效的疾病修饰疗法。随着PD患病率的上升以及社会迅速老龄化,需要更加重视康复治疗,其可与药物治疗相结合以减缓疾病进展。在本综述中,我们介绍了与PD运动功能、吞咽困难和言语障碍康复计划相关证据的最新情况。有氧运动、音乐疗法、舞蹈、虚拟现实和非侵入性脑刺激已被证明可改善运动功能,远程康复也可切实应用于PD。最近的研究分别表明,呼气肌强化训练和李·西尔弗曼嗓音疗法对吞咽困难和言语障碍有效。尽管已经尝试了许多康复计划,但证据仍然有限。未来需要设计良好的、有大量参与者的随机对照试验,以确立PD康复的证据。