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系统性硬化症的极早期诊断:解读疾病极早期阶段系统性硬化症的异质性

Very Early Diagnosis of Systemic Sclerosis: Deciphering the heterogeneity of systemic sclerosis in the very early stages of the disease.

作者信息

Lescoat Alain

机构信息

Department of Internal Medicine and Clinical Immunology, CHU Rennes, University of Rennes 1, Rennes, France.

CHU Rennes, Inserm, EHESP, Institut de Recherche en Santé, Environnement et Travail UMR_S 1085, Rennes, France.

出版信息

J Scleroderma Relat Disord. 2023 Feb;8(1):3-6. doi: 10.1177/23971983221129211. Epub 2022 Oct 11.

Abstract

The early diagnosis of systemic sclerosis has been a major challenge for the scleroderma community in the past 50 years. The recent publication of the predictive value of the VEDOSS (Very Early Diagnosis of Systemic Sclerosis) criteria in the in December 2021 has provided an unprecedented insight in the early stages of the disease. This editorial discusses the main findings from this 2021 VEDOSS publication and highlights key unanswered questions to be proposed on the research agenda in very early systemic sclerosis.

摘要

在过去50年里,系统性硬化症的早期诊断一直是硬皮病领域的一项重大挑战。2021年12月发表的关于系统性硬化症极早期诊断(VEDOSS)标准预测价值的研究,为该疾病的早期阶段提供了前所未有的见解。这篇社论讨论了2021年VEDOSS研究的主要发现,并强调了在系统性硬化症极早期研究议程上有待提出的关键未解决问题。

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