Russo Frank A, Mallik Adiel, Thomson Zoe, de Raadt St James Alexander, Dupuis Kate, Cohen Dan
Department of Psychology, Toronto Metropolitan University, Toronto, ON, Canada.
KITE, Toronto Rehabilitation Institute, University Health Network, Toronto, ON, Canada.
Front Digit Health. 2023 Jan 20;5:1064115. doi: 10.3389/fdgth.2023.1064115. eCollection 2023.
The greying of the world is leading to a rapid acceleration in both the healthcare costs and caregiver burden that are associated with dementia. There is an urgent need to develop new, easily scalable modalities of support. This perspective paper presents the theoretical background, rationale, and development plans for a music-based digital therapeutic to manage the neuropsychiatric symptoms of dementia, particularly agitation and anxiety. We begin by presenting the findings of a survey we conducted with key opinion leaders. The findings highlight the value of a music-based digital therapeutic for treating neuropsychiatric symptoms, particularly agitation and anxiety. We then consider the neural substrates of these neuropsychiatric symptoms before going on to evaluate randomized control trials on the efficacy of music-based interventions in their treatment. Finally, we present our development plans for the adaptation of an existing music-based digital therapeutic that was previously shown to be efficacious in the treatment of adult anxiety symptoms.
全球人口老龄化正导致与痴呆症相关的医疗保健成本和护理负担迅速增加。迫切需要开发新的、易于扩展的支持模式。这篇观点论文介绍了一种基于音乐的数字疗法的理论背景、基本原理和开发计划，该疗法用于管理痴呆症的神经精神症状，尤其是激越和焦虑。我们首先介绍我们对关键意见领袖进行的一项调查的结果。这些结果凸显了基于音乐的数字疗法在治疗神经精神症状，尤其是激越和焦虑方面的价值。然后，在继续评估基于音乐的干预措施治疗这些症状的疗效的随机对照试验之前，我们考虑这些神经精神症状的神经基础。最后，我们展示了对一种现有的基于音乐的数字疗法进行改编的开发计划，该疗法先前已被证明对治疗成人焦虑症状有效。
