Loh Huai Heng, Sukor Norlela
Department of Medicine, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia.
Department of Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center (UKMMC), Kuala Lumpur, Malaysia.
Clin Respir J. 2024 Mar;18(3):e13593. doi: 10.1111/crj.13593. Epub 2023 Feb 6.
Obstructive sleep apnea and vitamin D deficiency are associated with multiple complications with increased morbidity and mortality. However, the relationship between these two entities remains unclear, with clinical studies demonstrating contradictory results. This narrative review aims to present the current evidence and understanding of this relationship and discuss the possible mechanisms linking these two disease entities. Finally, we summarize and propose areas of opportunity for future research.
阻塞性睡眠呼吸暂停与维生素D缺乏均与多种并发症相关,会增加发病率和死亡率。然而,这两者之间的关系仍不明确,临床研究结果相互矛盾。本叙述性综述旨在介绍关于这种关系的现有证据和理解,并讨论将这两种疾病实体联系起来的可能机制。最后,我们总结并提出未来研究的机会领域。