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肯尼亚莫伊教学与转诊医院免费产妇保健服务对妊娠高血压疾病结局的影响:一项回顾性分析。

Impact of free maternity services on outcomes related to hypertensive disorders of pregnancy at Moi Teaching and Referral Hospital in Kenya: a retrospective analysis.

机构信息

School of Medicine, Department of Obstetrics and Gynecology, University of Toronto, 27 King's College Circle, Toronto, ON, M5S, Canada.

Moi Teaching and Referral Hospital, Eldoret, Kenya.

出版信息

BMC Pregnancy Childbirth. 2023 Feb 6;23(1):98. doi: 10.1186/s12884-023-05381-3.

Abstract

BACKGROUND

Preeclampsia is a major contributor to maternal and neonatal mortality worldwide. Ninety-nine percent of these deaths occur in resource limited settings. One of the greatest barriers to women seeking medical attention remains the cost of care. Kenya implemented a nation-wide policy change in 2013, offering free inpatient maternity services to all women to address this concern. Here, we explore the impact of this policy change on maternal and neonatal outcomes specific to the hypertensive disorders of pregnancy.

METHODS

We conducted a retrospective cross-sectional chart review of patients discharged or deceased with a diagnosis of gestational hypertension, preeclampsia, eclampsia or HELLP syndrome at a tertiary referral center in western Kenya one year before (June 1, 2012-May 31, 2013) and one year after (June 1, 2013-May 31, 2014) free maternity services were introduced at public facilities across the country. Demographic information, obstetric history, medical history, details of the current pregnancy, diagnosis on admission and at discharge, antepartum treatment, maternal outcomes, and neonatal outcomes were collected and comparisons were made between the time points.

RESULTS

There were more in hospital births after policy change was introduced. The proportion of women diagnosed with a hypertensive disorder of pregnancy was higher in the year before free maternity care although there was a statistically significant increase in the proportion of women diagnosed with gestational hypertension after policy change. Among those diagnosed with hypertensive disorders, there was no difference in the proportion who developed obstetric or medical complications. Of concern, there was a statistically significant increase in the proportion of women dying as a result of their condition. There was a statistically significant increase in the use of magnesium sulfate for seizure prophylaxis. There was no overall difference in the use of anti-hypertensives between groups and no overall difference in the proportion of women who received dexamethasone for fetal lung maturity.

CONCLUSIONS

Free maternity services, however necessary, are insufficient to improve maternal and neonatal outcomes related to the hypertensive disorders of pregnancy at a tertiary referral center in western Kenya. Multiple complementary strategies acting in unison are urgently needed.

摘要

背景

子痫前期是全球孕产妇和新生儿死亡的主要原因。这些死亡中有 99%发生在资源有限的环境中。妇女寻求医疗关注的最大障碍之一仍然是护理费用。肯尼亚于 2013 年实施了一项全国性政策变革,为所有妇女提供免费住院产妇服务,以解决这一问题。在这里,我们探讨了这一政策变革对肯尼亚西部一家三级转诊中心妊娠高血压、子痫前期、子痫或 HELLP 综合征等妊娠高血压疾病母婴结局的影响。

方法

我们对一家三级转诊中心的患者进行了回顾性横断面病历审查,这些患者在肯尼亚全国范围内公共设施提供免费产妇服务之前(2012 年 6 月 1 日-2013 年 5 月 31 日)和之后(2013 年 6 月 1 日-2014 年 5 月 31 日)出院或死亡,诊断为妊娠期高血压、子痫前期、子痫或 HELLP 综合征。收集人口统计学信息、产科病史、病史、当前妊娠详细信息、入院和出院时的诊断、产前治疗、产妇结局和新生儿结局,并比较两个时间点的差异。

结果

政策变革后,住院分娩的比例增加。在免费产妇护理之前,诊断为妊娠高血压疾病的妇女比例较高,尽管政策变革后诊断为妊娠期高血压的妇女比例有统计学意义上的显著增加。在诊断为高血压疾病的妇女中,发生产科或医疗并发症的比例没有差异。值得关注的是,由于病情而死亡的妇女比例有统计学意义上的显著增加。硫酸镁用于预防抽搐的使用率有统计学意义的增加。两组之间抗高血压药物的总体使用无差异,也没有总体上使用地塞米松促进胎儿肺成熟的比例差异。

结论

免费产妇服务虽然必要,但在肯尼亚西部一家三级转诊中心,不足以改善与妊娠高血压疾病相关的母婴结局。迫切需要采取多种互补策略协同作用。

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