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身体健康状况的聚类及其与同时存在的心理健康问题和饮酒问题的关联:一项横断面研究。

The clustering of physical health conditions and associations with co-occurring mental health problems and problematic alcohol use: a cross-sectional study.

机构信息

Department of Primary Care and Mental Health, University of Liverpool, Waterhouse Block B 1St Floor, 1-5 Brownlow St, Liverpool, L69 3G, UK.

School of Psychology, Ulster University, Belfast, UK.

出版信息

BMC Psychiatry. 2023 Feb 6;23(1):89. doi: 10.1186/s12888-023-04577-3.

Abstract

BACKGROUND

There is strong evidence for the co-occurrence of mental health conditions and alcohol problems, yet physical health outcomes among this group are not well characterised. This study aimed to identify clusters of physical health conditions and their associations with mental health and problematic alcohol use in England's general population.

METHODS

Cross-sectional analysis of the 2014 Adult Psychiatric Morbidity Survey (N = 7546) was conducted. The survey used standardised measures of problematic alcohol use and mental health conditions, including the Alcohol Use Disorders Identification Test (AUDIT) and the Clinical Interview Schedule-Revised. Participants self-reported any lifetime physical health conditions. Latent class analysis considered 12 common physical illnesses to identify clusters of multimorbidity. Multinomial logistic regression (adjusting for age, gender, ethnicity, education, and occupational grade) was used to explore associations between mental health, hazardous drinking (AUDIT 8 +), and co-occurring physical illnesses.

RESULTS

Five clusters were identified with statistically distinct and clinically meaningful disease patterns: 'Physically Healthy' (76.62%), 'Emerging Multimorbidity' (3.12%), 'Hypertension & Arthritis' (14.28%), 'Digestive & Bowel Problems'' (3.17%), and 'Complex Multimorbidity' (2.8%). Having a mental health problem was associated with increased odds of 'Digestive & Bowel Problems' (adjusted multinomial odds ratio (AMOR) = 1.58; 95% CI [1.15-2.17]) and 'Complex Multimorbidity' (AMOR = 2.02; 95% CI [1.49-2.74]). Individuals with co-occurring mental health conditions and problematic alcohol use also had higher odds of 'Digestive & Bowel Problems' (AMOR = 2.64; 95% CI [1.68-4.15]) and 'Complex Multimorbidity' (AMOR = 2.62; 95% CI [1.61-4.23]).

CONCLUSIONS

Individuals with a mental health condition concurrent with problematic alcohol use experience a greater burden of physical illnesses, highlighting the need for timely treatment which is likely to include better integration of alcohol and mental health services.

摘要

背景

心理健康状况和酒精问题同时存在的证据确凿,但该人群的身体健康状况却没有得到很好的描述。本研究旨在确定身体健康状况的聚类,并探讨其与英国普通人群中心理健康和酒精使用问题之间的关系。

方法

对 2014 年成人精神疾病调查(N=7546)进行横断面分析。该调查使用了酒精使用障碍识别测试(AUDIT)和临床访谈表修订版等标准化的酒精使用问题和心理健康状况测量工具。参与者自我报告了所有的终身身体健康状况。潜在类别分析考虑了 12 种常见的身体疾病,以确定多种疾病的聚类。使用多项逻辑回归(调整年龄、性别、种族、教育程度和职业等级)来探讨心理健康、危险饮酒(AUDIT 8+)和共患身体疾病之间的关系。

结果

共确定了五个具有统计学意义和临床意义的疾病模式不同的聚类:“身体健康”(76.62%)、“新兴多种疾病”(3.12%)、“高血压和关节炎”(14.28%)、“消化系统和肠道问题”(3.17%)和“复杂多种疾病”(2.8%)。患有心理健康问题与“消化系统和肠道问题”(调整后的多项逻辑回归比值比(AMOR)=1.58;95%置信区间 [1.15-2.17])和“复杂多种疾病”(AMOR=2.02;95%置信区间 [1.49-2.74])的患病风险增加相关。同时患有心理健康问题和酒精使用问题的个体,患“消化系统和肠道问题”(AMOR=2.64;95%置信区间 [1.68-4.15])和“复杂多种疾病”(AMOR=2.62;95%置信区间 [1.61-4.23])的风险也更高。

结论

同时患有心理健康问题和酒精使用问题的个体,身体疾病负担更重,这凸显了及时治疗的必要性,可能需要更好地整合酒精和心理健康服务。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5747/9901006/2988541b9cd8/12888_2023_4577_Fig1_HTML.jpg

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