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第一波新冠疫情后精神疾病结局的年龄特异性决定因素:一项加拿大在线队列研究的基线结果

Age-specific determinants of psychiatric outcomes after the first COVID-19 wave: baseline findings from a Canadian online cohort study.

作者信息

Stewart S Evelyn, Best John, Selles Robert, Naqqash Zainab, Lin Boyee, Lu Cynthia, Au Antony, Snell Gaelen, Westwell-Roper Clara, Vallani Tanisha, Ewing Elise, Dogra Kashish, Doan Quynh, Samji Hasina

机构信息

Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada.

British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.

出版信息

Child Adolesc Psychiatry Ment Health. 2023 Feb 6;17(1):20. doi: 10.1186/s13034-023-00560-8.

Abstract

BACKGROUND

Canadians endured unprecedented mental health (MH) and support access challenges during the first COVID-19 wave. Identifying groups of individuals who remain at risk beyond the acute pandemic phase is key to guiding systemic intervention efforts and policy. We hypothesized that determinants of three complementary, clinically actionable psychiatric outcomes would differ across Canadian age groups.

METHODS

The Personal Impacts of COVID-19 Survey (PICS) was iteratively developed with stakeholder feedback, incorporating validated, age-appropriate measures. Baseline, cross-sectional online data collected between November 2020-July 2021 was used in analyses. Age group-specific determinants were sought for three key baseline MH outcomes: (1) current probable depression, generalized anxiety disorder, obsessive-compulsive disorder and/or suicide attempt during COVID-19, (2) increased severity of any lifetime psychiatric diagnosis, and (3) inadequate MH support access during COVID-19. Multivariable logistic regression models were constructed for children, youth (self- and parent-report), young adults (19-29 years) and adults over 29 years, using survey type as a covariate. Statistical significance was defined by 95% confidence interval excluding an odds ratio of one.

RESULTS

Data from 3140 baseline surveys were analyzed. Late adolescence and early adulthood were identified as life phases with the worst MH outcomes. Poverty, limited education, home maker/caregiver roles, female and non-binary gender, LGBTQ2S + status and special educational, psychiatric and medical conditions were differentially identified as determinants across age groups.

INTERPRETATION

Negative psychiatric impacts of COVID-19 on Canadians that include poor access to MH support clearly persisted beyond the first wave, widening pre-existing inequity gaps. This should guide policy makers and clinicians in current and future prioritization efforts.

摘要

背景

在新冠疫情第一波期间,加拿大人经历了前所未有的心理健康(MH)问题以及获取支持方面的挑战。识别在急性疫情阶段之后仍处于风险中的人群,对于指导系统性干预措施和政策制定至关重要。我们假设,三种互补的、具有临床可操作性的精神科结局的决定因素在加拿大不同年龄组中会有所不同。

方法

新冠疫情个人影响调查(PICS)在利益相关者反馈的基础上进行了反复完善,纳入了经过验证的、适合不同年龄段的测量方法。分析使用了2020年11月至2021年7月期间收集的基线横断面在线数据。针对三个关键的基线心理健康结局,寻求特定年龄组的决定因素:(1)在新冠疫情期间当前可能存在的抑郁症、广泛性焦虑症、强迫症和/或自杀企图;(2)任何终生精神科诊断的严重程度增加;(3)在新冠疫情期间心理健康支持获取不足。使用调查类型作为协变量,为儿童、青少年(自我报告和家长报告)、年轻人(19 - 29岁)和29岁以上成年人构建多变量逻辑回归模型。统计学显著性定义为95%置信区间不包括比值比为1。

结果

对3140份基线调查数据进行了分析。青春期晚期和成年早期被确定为心理健康结局最差的生命阶段。贫困、教育程度有限、家庭主妇/照顾者角色、女性和非二元性别、LGBTQ2S + 身份以及特殊教育、精神科和医疗状况在不同年龄组中被差异识别为决定因素。

解读

新冠疫情对加拿大人的负面精神影响,包括难以获得心理健康支持,显然在第一波疫情之后仍然存在,扩大了先前存在的不平等差距。这应为政策制定者和临床医生当前及未来的优先事项提供指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c5f/9903565/63b898f84be1/13034_2023_560_Fig1_HTML.jpg

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