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腰椎假性痛风

Pseudogout of the lumbar spine.

作者信息

Gupta Sneha R, Cherukuri Sai Phani Sree, Chehab Mohamad, Paudel Kalyan, Haas Christopher

机构信息

Medstar Health Internal Medicine Residency Program, 3700 Toone Street, Apt 2622, Baltimore, MD 21224, USA.

Medstar Health Hospitalist Program, Baltimore, MD, USA.

出版信息

Radiol Case Rep. 2023 Feb 2;18(4):1490-1493. doi: 10.1016/j.radcr.2022.10.057. eCollection 2023 Apr.

Abstract

Calcium pyrophosphate deposition involves deposition of calcium pyrophosphate dihydrate crystals in various joints throughout the body. The term "pseudogout" refers to an acute attack of calcium pyrophosphate crystal-induced arthritis. Though clinical presentation and joint involvement vary, involvement of the lumbar spine is rare. We present the case of a 61-year-old male who presented with 3 days of worsening lower back pain. He had elevated inflammatory markers, leukocytosis, and spinal tenderness on exam. Magnetic resonance imaging of the lumbar spine showed likely L4-L5 osteomyelitis; however, biopsy of the disk space revealed extensive calcium pyrophosphate crystal deposition. The patient was treated with prednisone taper with alleviation of symptoms. Though pseudogout of the spine is rare, our report supports literature urging clinicians to consider pseudogout when assessing elderly patients with back pain for prompt and appropriate treatment.

摘要

焦磷酸钙沉积是指二水焦磷酸钙晶体在全身各个关节的沉积。“假性痛风”一词指的是焦磷酸钙晶体诱发的关节炎急性发作。虽然临床表现和关节受累情况各不相同,但腰椎受累情况罕见。我们报告一例61岁男性患者,其下背部疼痛加重3天。检查发现他炎症指标升高、白细胞增多且有脊柱压痛。腰椎磁共振成像显示可能为L4-L5骨髓炎;然而,椎间盘间隙活检显示有广泛的焦磷酸钙晶体沉积。患者接受泼尼松逐渐减量治疗后症状缓解。虽然脊柱假性痛风罕见,但我们的报告支持文献观点,即敦促临床医生在评估老年背痛患者时考虑假性痛风,以便及时进行适当治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/25e5/9898284/690737d94edf/gr1.jpg

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