Cardiac Electrophysiology Department, Saint Joseph Hospital, 1401 Harrodsburg Road, Lexington, KY 40504, USA.
Department of Internal Medicine, Gill Heart Institute, University of Kentucky, Lexington, KY, USA.
Europace. 2023 Mar 30;25(3):828-834. doi: 10.1093/europace/euad009.
Cardioversion is a very commonly performed procedure for persistent atrial fibrillation (AF). However, there is no well-defined protocol to address failed external electrical direct current cardioversion. The aim of the study is to test the efficacy of a pre-defined stepwise cardioversion protocol for patients with persistent AF of ≤12 months. Success was the achievement of sinus rhythm.
The study population included patients with persistent AF of ≤12 months duration requiring rhythm management. Patients were offered cardioversion using a pre-defined stepwise protocol using different electrode placement locations, applying compression at end of expiration, and higher energy delivered simultaneously through two defibrillators. : A total of 414 patients were included in the study, of which 362 (87.4%) required a single successful cardioversion. The remaining 52 (12.5%) patients required additional cardioversion attempts using the stepwise cardioversion protocol with an overall success rate of 99.3%. Two simultaneous defibrillators were required in 14 patients (3.4%). Patients with multiple cardioversions (13.5%) experienced more local skin irritation and pain compared with patients with single cardioversion (13.5% vs. 3.5%, P = 0.004). The predictor for the need for multiple cardioversion attempts is high body mass index, while high transthoracic impedance is associated with failed cardioversion. No major complications were observed during the study.
The stepwise cardioversion protocol has a high success rate of >99% and can be safely performed in outpatient or inpatient settings.
心脏转复是治疗持续性心房颤动(AF)非常常用的方法。然而,对于失败的体外直流电心脏转复,目前尚没有明确的方案。本研究旨在测试一种针对持续时间≤12 个月的持续性 AF 患者的预定义逐步心脏转复方案的疗效。成功是指窦性节律的实现。
研究人群包括需要节律管理的持续时间≤12 个月的持续性 AF 患者。患者接受预定义的逐步心脏转复方案,使用不同的电极放置位置、呼气末按压、同时通过两个除颤器传递更高的能量。共纳入 414 例患者,其中 362 例(87.4%)需要单次成功的心脏转复。其余 52 例(12.5%)患者需要使用逐步心脏转复方案进行额外的心脏转复尝试,总成功率为 99.3%。14 例患者(3.4%)需要使用两个同步除颤器。与单次心脏转复相比,多次心脏转复的患者(13.5%)经历更多的局部皮肤刺激和疼痛(13.5%比 3.5%,P=0.004)。需要多次心脏转复尝试的预测因素是高体重指数,而高胸阻抗与心脏转复失败相关。研究期间未观察到主要并发症。
逐步心脏转复方案的成功率>99%,可在门诊或住院环境中安全进行。