头孢呋辛酯治疗复发性尿路感染的对比试验表明6周随访的重要性。
Comparative trial of cefuroxime axetil in recurrent urinary tract infections illustrating importance of 6-week follow-up.
作者信息
Brumfitt W, Hamilton-Miller J M, Smith G W
机构信息
Department of Medical Microbiology, Royal Free Hospital, School of Medicine, Hampstead, London, England.
出版信息
Antimicrob Agents Chemother. 1987 Sep;31(9):1442-3. doi: 10.1128/AAC.31.9.1442.
Abstract
Women with recurrent urinary tract infections treated with cefuroxime axetil (500 or 250 mg twice daily) for 7 days had a higher relapse rate when tested 6 weeks after the start of treatment than those given amoxycillin (250 mg three times daily). The poor performance of cefuroxime axetil is explained by variable bioavailability.
摘要
复发性尿路感染女性患者接受头孢呋辛酯（500毫克或250毫克，每日两次）治疗7天，在治疗开始6周后进行检测时，其复发率高于接受阿莫西林（250毫克，每日三次）治疗的患者。头孢呋辛酯疗效不佳的原因是其生物利用度不稳定。
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