Griffin Samuel, Cleary Ryan T, Prim Michael, Musgrave Nicholas, Coppens Jeroen R, Kemp Joanna
1Department of Neurosurgery, St. Louis University School of Medicine, St. Louis, Missouri; and.
2Department of Neurosurgery, Washington University School of Medicine, St. Louis, Missouri.
J Neurosurg Case Lessons. 2023 Feb 6;5(6). doi: 10.3171/CASE22423.
The novel coronavirus disease 2019 (COVID-19) can be associated with various neurological manifestations, including cerebrovascular disease, seizures, peripheral nerve disease, and encephalitis. Intracranial abscess related to COVID-19 is rare but illustrates a serious complication in the studied cases.
The authors report 3 cases of patients presenting with COVID-19 complicated by sinusitis with associated intracranial abscesses. Each patient underwent craniotomy with washout and sinus debridement during their hospital stay. All 3 patients improved to their baseline following treatment. Similar outcomes have been observed in other cases of intracranial abscess associated with COVID-19 infections.
Patients achieved significant improvement following evacuation of the abscess and intravenous antibiotics. Further investigation is needed to determine treatment in relation to COVID-19, and the authors recommend following the standard treatment of intracranial abscess at this time.
2019年新型冠状病毒病（COVID-19）可伴有多种神经表现，包括脑血管疾病、癫痫发作、周围神经疾病和脑炎。与COVID-19相关的颅内脓肿罕见，但在所研究的病例中显示出一种严重并发症。
作者报告了3例COVID-19合并鼻窦炎及相关颅内脓肿的患者。每位患者在住院期间均接受了开颅冲洗和鼻窦清创术。所有3例患者治疗后均恢复至基线状态。在其他与COVID-19感染相关的颅内脓肿病例中也观察到了类似结果。
脓肿引流和静脉使用抗生素后患者有显著改善。需要进一步研究以确定针对COVID-19的治疗方法，作者建议目前遵循颅内脓肿的标准治疗方法。
