Department of Pharmacy, Guru Gobind Singh College of Pharmacy, Yamuna Nagar, 135001, Haryana, India.
Endocr Metab Immune Disord Drug Targets. 2023;23(9):1125-1136. doi: 10.2174/1871530323666230207123613.
Bakuchiol, is a principal bioactive component present in seeds of Psoralea corylifolia. It is one of the important monoterpene phenols and has been reported to possess extensive pharmacological properties like antioxidant, anti-inflammatory, anticancer, and hepatoprotective. Bakuchiol also plays a significant role in mental disorders. With an aim to explore the pharmacological potential of plant Psoralea corylifolia and its bioactive constituent, Bakuchiol; which may act as a lead to develop new molecular entities as drugs. A substantial literature survey was performed by scientific search engines like PubMed, Scopus,Web of Science, Science Direct, etc., and were reviewed with particular emphasis on their scientific impact and novelty. The study concludes that both Psoralea and bakuchiol possess innumerable pharmacological potentials to treat multiple disorders. Altogether, the promising pharmacological activities of bakuchiol may open new probes for therapeutic invention in the management of numerous ailments. Thus, the present review gives the erudition of bakuchiol as d foundation for further studies on the molecular mechanisms of BXXXD in the treatment of T2DM.
补骨脂酚是补骨脂种子中的主要生物活性成分。它是一种重要的单萜酚类化合物，据报道具有广泛的药理学特性，如抗氧化、抗炎、抗癌和保肝。补骨脂酚在精神障碍中也起着重要作用。本研究旨在探索植物补骨脂及其生物活性成分补骨脂酚的药理学潜力，它可能成为开发新的分子实体作为药物的先导。通过 PubMed、Scopus、Web of Science、Science Direct 等科学搜索引擎进行了大量的文献调查，并特别强调了它们的科学影响和新颖性。该研究得出的结论是，补骨脂和补骨脂酚都具有治疗多种疾病的无数药理学潜力。总之，补骨脂酚有希望的药理学活性可能为治疗许多疾病的治疗发明开辟新的途径。因此，本综述提供了补骨脂酚的知识基础，以便进一步研究 BXXXD 在治疗 T2DM 中的分子机制。
