经皮肝穿刺活检后的发病率。
Morbidity after percutaneous liver biopsy.
作者信息
Lichtman S, Guzman C, Moore D, Weber J L, Roberts E A
机构信息
Division of Gastroenterology, Hospital for Sick Children, Toronto, Canada.
出版信息
Arch Dis Child. 1987 Sep;62(9):901-4. doi: 10.1136/adc.62.9.901.
The safety of percutaneous liver biopsy with a 1.2 mm Menghini needle in infants aged one year or less was investigated. One hundred and eighty four procedures performed from 1975 to 1985 were reviewed. There were no deaths or major complications within 48 hours associated with the procedure. In five instances specific complications occurred: a drop in haemoglobin concentration (three), transient hypotension (one), and haematoma at the biopsy site (one). The result of liver biopsy was diagnostic in 83% of cases, compatible with unspecified metabolic disease in 8%, and normal or not diagnostic in 9%. This study suggests that percutaneous liver biopsy can be performed with relative safety in small infants if coagulation is normal and there are no major contraindications, and the results yield important diagnostic information which cannot be obtained using less invasive procedures.
对1岁及以下婴儿使用1.2毫米Menghini针进行经皮肝穿刺活检的安全性进行了研究。回顾了1975年至1985年期间进行的184例手术。在48小时内没有与该手术相关的死亡或重大并发症。有5例出现了特定并发症：血红蛋白浓度下降（3例）、短暂性低血压（1例）和活检部位血肿（1例）。肝活检结果在83%的病例中具有诊断价值，8%与未明确的代谢性疾病相符，9%为正常或无诊断意义。这项研究表明，如果凝血功能正常且无重大禁忌证，在小婴儿中进行经皮肝穿刺活检相对安全，其结果可提供重要的诊断信息，而这些信息无法通过侵入性较小的检查获得。
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