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Data and subject heterogeneity and data sharing: keys to translational success in spinal cord injury research?

作者信息

Fouad Karim, Wireman Olivia H, Gensel John C

机构信息

Faculty of Rehabilitation Medicine, Department of Physical Therapy, Neuroscience and Mental Health Institute, University of Alberta, Alberta, Canada.

Spinal Cord and Brain Injury Research Center (SCoBIRC), Department of Physiology, University of Kentucky College of Medicine, Lexington, KY, USA.

出版信息

Neural Regen Res. 2023 Aug;18(8):1730-1731. doi: 10.4103/1673-5374.363191.

DOI:10.4103/1673-5374.363191
PMID:36751797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10154489/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/10154489/d8fc023243d9/NRR-18-1730-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/10154489/d8fc023243d9/NRR-18-1730-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/14af/10154489/d8fc023243d9/NRR-18-1730-g001.jpg

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本文引用的文献

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Advanced Age and Neurotrauma Diminish Glutathione and Impair Antioxidant Defense after Spinal Cord Injury.高龄和神经创伤会降低脊髓损伤后的谷胱甘肽水平并损害抗氧化防御。
J Neurotrauma. 2022 Aug;39(15-16):1075-1089. doi: 10.1089/neu.2022.0010. Epub 2022 Jul 13.
2
Immunoglobulin G Is Increased in the Injured Spinal Cord in a Sex- and Age-Dependent Manner.免疫球蛋白 G 在损伤的脊髓中呈性别和年龄依赖性增加。
J Neurotrauma. 2022 Aug;39(15-16):1090-1098. doi: 10.1089/neu.2022.0011. Epub 2022 Jul 13.
3
Mitochondria exert age-divergent effects on recovery from spinal cord injury.
线粒体对脊髓损伤后的恢复有年龄差异的影响。
Exp Neurol. 2021 Mar;337:113597. doi: 10.1016/j.expneurol.2021.113597. Epub 2021 Jan 7.
4
Considerations for Studying Sex as a Biological Variable in Spinal Cord Injury.将性别作为脊髓损伤生物学变量进行研究的考量因素
Front Neurol. 2020 Aug 5;11:802. doi: 10.3389/fneur.2020.00802. eCollection 2020.
5
FAIR SCI Ahead: The Evolution of the Open Data Commons for Pre-Clinical Spinal Cord Injury Research.公平科学前进:临床前脊髓损伤研究开放数据共同体的演变。
J Neurotrauma. 2020 Mar 15;37(6):831-838. doi: 10.1089/neu.2019.6674. Epub 2019 Dec 6.
6
Developing a data sharing community for spinal cord injury research.建立一个用于脊髓损伤研究的数据共享社区。
Exp Neurol. 2017 Sep;295:135-143. doi: 10.1016/j.expneurol.2017.05.012. Epub 2017 May 30.
7
The FAIR Guiding Principles for scientific data management and stewardship.科学数据管理和保存的 FAIR 指导原则。
Sci Data. 2016 Mar 15;3:160018. doi: 10.1038/sdata.2016.18.
8
Traumatic spinal cord injury in the United States, 1993-2012.1993 - 2012年美国创伤性脊髓损伤情况
JAMA. 2015 Jun 9;313(22):2236-43. doi: 10.1001/jama.2015.6250.
9
N-acetylcysteine amide preserves mitochondrial bioenergetics and improves functional recovery following spinal trauma.N-乙酰半胱氨酸酰胺可维持创伤性脊髓损伤后的线粒体生物能量代谢并改善功能恢复。
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