• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肌病综合征揭示一种罕见疾病:希恩综合征,基于病例的综述。

Myopathic syndrome revealing a rare condition: Sheehan syndrome, a case-based review.

机构信息

Department of Internal Medicine and Rheumatology, Sfanta Maria" Hospital, 011172, Bucharest, Romania.

Department of Internal Medicine and Rheumatology, Carol Davila University of Medicine and Pharmacy, 050474, Bucharest, Romania.

出版信息

Clin Rheumatol. 2023 Jun;42(6):1705-1712. doi: 10.1007/s10067-023-06535-6. Epub 2023 Feb 9.

DOI:10.1007/s10067-023-06535-6
PMID:36757535
Abstract

This report presents a case of a Sheehan syndrome diagnosed with a delay of 29 years after occurrence of first symptoms, following a laborious birth ended with dead fetus and massive hemorrhage. The 50-year-old patient, with early menopause from the age of 21, is referred to our rheumatology department to investigate the etiology of a myopathic syndrome, which started 2 months before and gradually worsened. The differential diagnosis took into consideration the autoimmune, infectious, paraneoplastic, endocrinological, and drug-induced myopathic syndrome. Paraclinical investigations revealed panhypopituitarism, and cerebral magnetic resonance imaging detected empty-sella. The etiology of a myopathic syndrome is often multifactorial; therefore, it is important to continue the investigations even after identifying one possible etiological factor, especially when it does not seem to fully explain the clinical-paraclinical picture. Usually, the multiple dimensions of panhypopituitarism bring the patient to various medical specialties depending on the dominant symptomatology. Given the rarity of the above-mentioned syndrome in the present, and the long gap between the initial event and the final diagnosis, its identification continues to be a challenge.

摘要

本报告介绍了一例希恩氏综合征病例,该患者在首次出现症状后 29 年才被诊断出来,此前发生了一次难产,导致死胎和大量出血。这位 50 岁的患者在 21 岁时就出现了早期绝经,因肌肉疾病而被转诊至我们的风湿病科,以调查发病原因,该疾病始于 2 个月前,并逐渐恶化。鉴别诊断考虑了自身免疫性、感染性、副肿瘤性、内分泌性和药物诱导性肌病综合征。临床检查发现全垂体功能减退症,脑部磁共振成像显示空蝶鞍。肌病的病因通常是多因素的;因此,即使确定了一个可能的病因,也很有必要继续进行调查,特别是当它似乎不能完全解释临床-临床检查结果时。通常,全垂体功能减退症的多个方面会根据主要症状使患者就诊于不同的医学专业。鉴于目前这种综合征非常罕见,且初始事件与最终诊断之间存在很长的时间间隔,因此识别它仍然是一个挑战。

相似文献

1
Myopathic syndrome revealing a rare condition: Sheehan syndrome, a case-based review.肌病综合征揭示一种罕见疾病:希恩综合征,基于病例的综述。
Clin Rheumatol. 2023 Jun;42(6):1705-1712. doi: 10.1007/s10067-023-06535-6. Epub 2023 Feb 9.
2
[A 36-year old female patient presenting with hypoglycemic coma].一名36岁女性患者,出现低血糖昏迷。
Internist (Berl). 2009 May;50(5):606-11. doi: 10.1007/s00108-008-2277-7.
3
[Severe hyponatremia secondary to panhypopituitarism in a patient with primary empty sella turcica syndrome].[一例原发性空蝶鞍综合征患者继发于全垂体功能减退的严重低钠血症]
An Med Interna. 1999 Oct;16(10):546-7.
4
[Panhypopituitarism disclosing empty sella turcica syndrome].[全垂体功能减退症伴空蝶鞍综合征]
Rev Med Interne. 1998 Aug;19(8):565-7. doi: 10.1016/s0248-8663(99)80024-1.
5
A case of postpartum hypopituitarism associated with empty sella: possible relation to postpartum autoimmune hypophysitis.一例与空蝶鞍相关的产后垂体功能减退症:可能与产后自身免疫性垂体炎有关。
Endocr J. 1993 Aug;40(4):431-8. doi: 10.1507/endocrj.40.431.
6
[Three patients with hypopituitarism accompanied by primary empty sella presenting mental symptoms].[三例垂体功能减退症伴原发性空蝶鞍患者出现精神症状]
Rinsho Shinkeigaku. 1989 Aug;29(8):1023-7.
7
Empty sella syndrome associated with partial hypopituitarism (visualized on MRI scan).与部分垂体功能减退相关的空蝶鞍综合征(磁共振成像扫描显示)。
J Am Osteopath Assoc. 1992 Sep;92(9):1172-4.
8
A case of Sheehan's syndrome associated with severe anemia and empty sella proved 48 years after postpartum hemorrhage.一例希恩综合征合并严重贫血及空蝶鞍,于产后出血48年后确诊。
Endocr J. 1995 Dec;42(6):803-9. doi: 10.1507/endocrj.42.803.
9
Primary empty sella syndrome with panhypopituitarism in a child.一名儿童患原发性空蝶鞍综合征伴全垂体功能减退。
Helv Paediatr Acta. 1984 Dec;39(5-6):473-9.
10
Symptomatic hypopituitarism revealing a primary empty sella turcica.症状性垂体功能减退症揭示了原发性空蝶鞍综合征。
Postgrad Med J. 1981 Apr;57(666):235-7. doi: 10.1136/pgmj.57.666.235.

本文引用的文献

1
A 45-year-old female patient with Sheehan's syndrome presenting with imminent adrenal crisis: a case report.一位 45 岁女性希恩氏综合征患者,表现为即将发生的肾上腺危象:病例报告。
J Med Case Rep. 2021 May 8;15(1):229. doi: 10.1186/s13256-021-02827-0.
2
Sheehan's syndrome as a mimic of premature ovarian insufficiency: need for advocacy.席汉综合征伪装成卵巢早衰:需要宣传。
Climacteric. 2021 Oct;24(5):526. doi: 10.1080/13697137.2021.1905626. Epub 2021 Apr 8.
3
Urinary tract infection is associated with hypokalemia: a case control study.
尿路感染与低钾血症相关:一项病例对照研究。
BMC Urol. 2020 Jul 20;20(1):108. doi: 10.1186/s12894-020-00678-3.
4
A case of acute Sheehan's syndrome and literature review: a rare but life-threatening complication of postpartum hemorrhage.1例急性希恩综合征病例及文献复习:产后出血罕见但危及生命的并发症
BMC Pregnancy Childbirth. 2017 Jun 14;17(1):188. doi: 10.1186/s12884-017-1380-y.
5
Protracted delirium with Sheehan's syndrome.席汉综合征伴持续性谵妄
Acta Neuropsychiatr. 2012 Jun;24(3):183-5. doi: 10.1111/j.1601-5215.2011.00614.x.
6
Sheehan's syndrome: new insights into an old disease.希恩综合征:对一种古老疾病的新见解。
Endocrine. 2016 Jan;51(1):22-31. doi: 10.1007/s12020-015-0726-3. Epub 2015 Sep 1.
7
Sheehan's syndrome with reversible dilated cardiomyopathy: A case report and brief overview.席汉综合征合并可逆性扩张型心肌病:一例报告及简要概述。
J Saudi Heart Assoc. 2014 Apr;26(2):117-20. doi: 10.1016/j.jsha.2014.01.005. Epub 2014 Jan 27.
8
[Sheehan's syndrome after obstetric hemorrhage].[产科出血后席汉综合征]
Rev Esp Anestesiol Reanim. 2014 Dec;61(10):575-8. doi: 10.1016/j.redar.2014.01.012. Epub 2014 Mar 15.
9
A case of Sheehan's syndrome that manifested as bilateral ptosis.一例表现为双侧上睑下垂的席汉氏综合征。
J Korean Med Sci. 2011 Apr;26(4):580-2. doi: 10.3346/jkms.2011.26.4.580. Epub 2011 Mar 28.
10
A case report of Sheehan's syndrome with acute onset, hyponatremia and severe anemia.希恩综合征伴急性起病、低钠血症和严重贫血的病例报告。
Acta Biomed. 2009 Apr;80(1):73-6.