Altenbernd Jens, Kutta Felix, Forsting Michael, Theysohn Jens, Rohde Stefan
Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Hufelandstr. 22, 45122, Essen, Germany.
Radiology and Neuroradiology, Klinikum Dortmund gGmbH, Dortmund, Germany.
CVIR Endovasc. 2023 Feb 10;6(1):5. doi: 10.1186/s42155-023-00352-3.
In recent years sclerotherapy has increasingly become the treatment of choice for peripheral slow-flow malformations. However, the long-term effectiveness of sclerotherapy is still a matter of debate, especially when it comes to new sclerosing agents like polidocanol. This study aims at gathering further information concerning its long-term effectiveness and safety.
Most patients reported a reduction of symptoms which include pain (57,7%), swelling (65,4%) and functional impairment (60%). Cosmetic complaints were less likely to be reduced by sclerotherapy (44,4%). In most cases a relief of symptoms was stable for many years, especially after several consecutive treatment sessions. Complication rates were comparably low, with only 2 patients requiring additional treatment at hospital and no lasting damages. (…) (7) Most patients (70,9%) were at least partially satisfied with the treatment. Satisfaction was closely linked to a partial or complete relief of symptoms (p = 0.001).
Sclerotherapy is a promising way of treating slow-flow-malformations. Polidocanol has proved to be a save sclerosing agent. The reduction of major symptoms was substantial in most cases and lasted for many years.
近年来,硬化疗法越来越成为外周缓慢血流畸形的首选治疗方法。然而,硬化疗法的长期有效性仍存在争议,尤其是在涉及到像聚多卡醇这样的新型硬化剂时。本研究旨在收集有关其长期有效性和安全性的更多信息。
大多数患者报告症状减轻,包括疼痛(57.7%)、肿胀(65.4%)和功能障碍(60%)。硬化疗法不太可能减轻美容方面的问题(44.4%)。在大多数情况下,症状缓解多年来一直稳定,尤其是在连续多次治疗后。并发症发生率相对较低,只有2名患者需要住院接受额外治疗,且无持久损伤。(…)(7)大多数患者(70.9%)至少对治疗部分满意。满意度与症状部分或完全缓解密切相关(p = 0.001)。
硬化疗法是治疗缓慢血流畸形的一种有前景的方法。聚多卡醇已被证明是一种安全的硬化剂。在大多数情况下,主要症状的减轻幅度很大,且持续多年。