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[胆碱能系统在急性低压缺氧恢复期的参与情况]

[Participation of cholinergic systems in the recovery period following acute hypobaric hypoxia].

作者信息

Alybaev A M, Bobkov Iu G, Losev A S

出版信息

Biull Eksp Biol Med. 1987 Oct;104(10):466-9.

PMID:3676472
Abstract

The influence of some cholinergic drugs has been studied during prophylactic treatment and the recovery period after acute hypobaric hypoxia (AHBH) on AHBH model. Cholinolytics and cholinomimetics were shown to produce different effects on the animal resistance to AHBH, their role in the formation of resistance to hypoxia depending on the type of animal, the extent of hypoxic damage and duration of the recovery period after primary AHBH. The experiments performed suggest an important role of cholinergic system in the formation of hypoxic resistance in animals.

摘要

在急性低压缺氧(AHBH)模型的预防性治疗和恢复期,研究了某些胆碱能药物的影响。结果表明,抗胆碱药和拟胆碱药对动物抵抗AHBH的能力产生不同影响,它们在缺氧抗性形成中的作用取决于动物类型、缺氧损伤程度以及初次AHBH后恢复期的时长。所进行的实验表明胆碱能系统在动物缺氧抗性形成中起重要作用。

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