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本文引用的文献

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Co-Targeting Luminal B Breast Cancer with S-Adenosylmethionine and Immune Checkpoint Inhibitor Reduces Primary Tumor Growth and Progression, and Metastasis to Lungs and Bone.联合使用S-腺苷甲硫氨酸和免疫检查点抑制剂靶向治疗管腔B型乳腺癌可减少原发性肿瘤的生长、进展以及向肺和骨的转移。
Cancers (Basel). 2022 Dec 22;15(1):48. doi: 10.3390/cancers15010048.
2
A Retrospective, Single-Institution Experience of Bullous Pemphigoid as an Adverse Effect of Immune Checkpoint Inhibitors.大疱性类天疱疮作为免疫检查点抑制剂不良反应的单机构回顾性研究经验
Cancers (Basel). 2022 Nov 5;14(21):5451. doi: 10.3390/cancers14215451.
3
Tumor-Infiltrating Lymphocytes (TILs) in Epithelial Ovarian Cancer: Heterogeneity, Prognostic Impact, and Relationship with Immune Checkpoints.上皮性卵巢癌中的肿瘤浸润淋巴细胞（TILs）：异质性、预后影响及与免疫检查点的关系
Cancers (Basel). 2022 Oct 29;14(21):5332. doi: 10.3390/cancers14215332.
4
Checkpoint Inhibitors in Cancer Therapy: Clinical Benefits for Head and Neck Cancers.癌症治疗中的检查点抑制剂：对头颈部癌症的临床益处
Cancers (Basel). 2022 Oct 11;14(20):4985. doi: 10.3390/cancers14204985.
5
Oncolytic Adenoviruses: The Cold War against Cancer Finally Turns Hot.溶瘤腺病毒：对抗癌症的冷战终于升温。
Cancers (Basel). 2022 Sep 27;14(19):4701. doi: 10.3390/cancers14194701.
6
Incorporating Immunotherapy in the Management of Gastric Cancer: Molecular and Clinical Implications.免疫疗法在胃癌治疗中的应用：分子与临床意义
Cancers (Basel). 2022 Sep 8;14(18):4378. doi: 10.3390/cancers14184378.
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Radiomic Signatures Associated with CD8 Tumour-Infiltrating Lymphocytes: A Systematic Review and Quality Assessment Study.与CD8肿瘤浸润淋巴细胞相关的影像组学特征：一项系统评价和质量评估研究
Cancers (Basel). 2022 Jul 27;14(15):3656. doi: 10.3390/cancers14153656.
8
Immune Checkpoint Inhibitors in Cancer Therapy-How to Overcome Drug Resistance?癌症治疗中的免疫检查点抑制剂——如何克服耐药性？
Cancers (Basel). 2022 Jul 22;14(15):3575. doi: 10.3390/cancers14153575.
9
Comprehensive Genomic Profiling Reveals Clinical Associations in Response to Immune Therapy in Head and Neck Cancer.综合基因组分析揭示头颈部癌免疫治疗反应中的临床关联。
Cancers (Basel). 2022 Jul 18;14(14):3476. doi: 10.3390/cancers14143476.
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Is the Efficacy of Adding Ramucirumab to Docetaxel Related to a History of Immune Checkpoint Inhibitors in the Real-World Clinical Practice?在真实世界临床实践中，将雷莫西尤单抗添加到多西他赛中的疗效与免疫检查点抑制剂治疗史有关吗？
Cancers (Basel). 2022 Jun 16;14(12):2970. doi: 10.3390/cancers14122970.

癌症治疗中的免疫检查点抑制剂——我们如何提高临床获益？

Immune Checkpoint Inhibitors in Cancer Therapy-How Can We Improve Clinical Benefits?

作者信息

Baxevanis Constantin N

机构信息

Cancer Immunology and Immunotherapy Center, Cancer Research Center, Saint Savas Cancer Hospital, 11522 Athens, Greece.

出版信息

Cancers (Basel). 2023 Jan 31;15(3):881. doi: 10.3390/cancers15030881.

DOI:10.3390/cancers15030881
PMID:36765836
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9913410/
Abstract

Immune checkpoint inhibitors (ICIs) are in the spotlight of cancer treatment by increasing the probability for long-term survival in patients with metastatic disease and by considerably prolonging progression-free survival in patients at early disease stages [...].

摘要

免疫检查点抑制剂（ICIs）因提高转移性疾病患者的长期生存概率以及显著延长疾病早期患者的无进展生存期，而成为癌症治疗的焦点[……]。