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特刊介绍:“骨骼肌萎缩:细胞水平的机制”

Introduction to the Special Issue "Skeletal Muscle Atrophy: Mechanisms at a Cellular Level".

机构信息

Department of Biomedical Sciences (DBS), University of Padova, 35128 Padova, Italy.

Veneto Institute of Molecular Medicine (VIMM), 35128 Padova, Italy.

出版信息

Cells. 2023 Feb 3;12(3):502. doi: 10.3390/cells12030502.

DOI:10.3390/cells12030502
PMID:36766844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9914442/
Abstract

Skeletal muscle is the most abundant tissue in the body and requires high levels of energy to function properly. Skeletal muscle allows voluntary movement and body posture, which require different types of fiber, innervation, energy, and metabolism. Here, we summarize the contribution received at the time of publication of this Introductory Issue for the Special Issue dedicated to "". The Special Issue is divided into three sections. The first is dedicated to skeletal muscle pathophysiology, the second to disease mechanisms, and the third to therapeutic development.

摘要

骨骼肌是人体中最丰富的组织,需要高水平的能量才能正常运作。骨骼肌允许自愿运动和身体姿势,这需要不同类型的纤维、神经支配、能量和代谢。在这里,我们总结了在本期特刊“”出版时收到的贡献。该特刊分为三个部分。第一部分专门讨论骨骼肌的病理生理学,第二部分专门讨论疾病机制,第三部分专门讨论治疗开发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8421/9914442/aaa9c75f0637/cells-12-00502-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8421/9914442/197efdf7d330/cells-12-00502-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8421/9914442/aaa9c75f0637/cells-12-00502-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8421/9914442/197efdf7d330/cells-12-00502-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8421/9914442/aaa9c75f0637/cells-12-00502-g002.jpg

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本文引用的文献

1
Correction: Lee et al. Protein Arginine Methyltransferases in Neuromuscular Function and Diseases. 2022, , 364.更正:李等人。蛋白质精氨酸甲基转移酶在神经肌肉功能和疾病中的作用。2022年,第364页。
Cells. 2022 Aug 22;11(16):2609. doi: 10.3390/cells11162609.
2
Metabolic Pathways and Ion Channels Involved in Skeletal Muscle Atrophy: A Starting Point for Potential Therapeutic Strategies.涉及骨骼肌萎缩的代谢途径和离子通道:潜在治疗策略的起点。
Cells. 2022 Aug 18;11(16):2566. doi: 10.3390/cells11162566.
3
VMP1 Regulated by chi-miR-124a Effects Goat Myoblast Proliferation, Autophagy, and Apoptosis through the PI3K/ULK1/mTOR Signaling Pathway.
chi-miR-124a 通过调控 VMP1 影响山羊肌细胞增殖、自噬和凋亡的机制研究。
Cells. 2022 Jul 18;11(14):2227. doi: 10.3390/cells11142227.
4
Skeletal Muscle Pathogenesis in Polyglutamine Diseases.多聚谷氨酰胺疾病中的骨骼肌发病机制。
Cells. 2022 Jul 3;11(13):2105. doi: 10.3390/cells11132105.
5
Leucine-Rich Diet Improved Muscle Function in Cachectic Walker 256 Tumour-Bearing Wistar Rats.富含亮氨酸的饮食可改善恶病质 Walker 256 肿瘤荷瘤 Wistar 大鼠的肌肉功能。
Cells. 2021 Nov 23;10(12):3272. doi: 10.3390/cells10123272.
6
Extract Ameliorates Muscle Atrophy in Streptozotocin-Induced Diabetic Mice by Downregulation of the CREB-KLF15 and Autophagy-Lysosomal Pathways.提取物通过下调 CREB-KLF15 和自噬溶酶体途径改善链脲佐菌素诱导的糖尿病小鼠的肌肉萎缩。
Cells. 2021 Sep 2;10(9):2283. doi: 10.3390/cells10092283.
7
Concurrent BMP Signaling Maintenance and TGF-β Signaling Inhibition Is a Hallmark of Natural Resistance to Muscle Atrophy in the Hibernating Bear.在冬眠熊中,BMP 信号的持续激活和 TGF-β 信号的抑制是天然抵抗肌肉萎缩的标志。
Cells. 2021 Jul 23;10(8):1873. doi: 10.3390/cells10081873.
8
Master Regulators of Muscle Atrophy: Role of Costamere Components.肌肉萎缩的主要调节因子:质膜力学感受器成分的作用。
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9
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10
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Cells. 2020 Dec 2;9(12):2582. doi: 10.3390/cells9122582.