Geriatric Medicine Department, Hospital Universitario de la Ribera, Carretera de Corbera km. 1, 46600 Alzira, Spain.
Centro de Investigación Biomédica en Red Fragilidad y Envejecimiento Saludable (CIBERFES), 28029 Madrid, Spain.
Int J Environ Res Public Health. 2023 Jan 17;20(3):1678. doi: 10.3390/ijerph20031678.
Frailty is prevalent in older adults and is related to a worsening functionality, quality of life, and health outcomes. Though there is an increasing interest in this field, the relationship between frailty and worsening COPD outcomes remains unknown. A narrative review of the literature with studies published between 2018 and 2022 was carried out to address three questions: the prevalence of frailty and other geriatric syndromes in COPD patients, the link between frailty and worsening health outcomes in COPD patients, and the non-pharmacological interventions performed in order to reverse frailty in these patients. A total of 25 articles were selected. Frailty prevalence ranged from 6% and 85.9%, depending on the COPD severity and the frailty measurement tool used. Frailty in COPD patients was related to a high prevalence of geriatric syndromes and to a high incidence of adverse events such as exacerbations, admissions, readmissions, and mortality. One study showed improvements in functionality after physical intervention. In conclusion, the prevalence of frailty is associated with a high incidence of geriatric syndromes and adverse events in COPD patients. The use of frailty screenings and a comprehensive geriatric assessment of COPD patients is advisable in order to detect associated problems and to establish individualized approaches for better outcomes.
衰弱在老年人中很常见，与功能恶化、生活质量下降和健康结果不良有关。尽管人们对这一领域越来越感兴趣，但衰弱与 COPD 结果恶化之间的关系仍不清楚。对 2018 年至 2022 年期间发表的研究进行了文献综述，以回答三个问题：COPD 患者中衰弱和其他老年综合征的流行情况、衰弱与 COPD 患者健康结果恶化之间的联系，以及为逆转这些患者的衰弱而进行的非药物干预措施。共选择了 25 篇文章。衰弱的流行率因 COPD 的严重程度和使用的衰弱测量工具而异，范围为 6%至 85.9%。COPD 患者的衰弱与老年综合征的高患病率以及诸如加重、住院、再住院和死亡等不良事件的高发率相关。一项研究表明，物理干预后功能得到改善。总之，衰弱在 COPD 患者中的流行率与老年综合征和不良事件的高发率相关。建议对 COPD 患者进行衰弱筛查和全面的老年评估，以发现相关问题并为更好的结果制定个体化的方法。
