Institute of Experimental and Translational Cardiac Imaging, DZHK, Centre for Cardiovascular Imaging, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany.
Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, 60590 Frankfurt am Main, Germany.
Int J Environ Res Public Health. 2023 Jan 26;20(3):2201. doi: 10.3390/ijerph20032201.
Human immunodeficiency virus (HIV) infection is a leading cause of mortality and morbidity worldwide. The introduction of antiretroviral therapy (ART) has significantly reduced the risk of developing acquired immune deficiency syndrome and increased life expectancy, approaching that of the general population. However, people living with HIV have a substantially increased risk of cardiovascular diseases despite long-term viral suppression using ART. HIV-associated cardiovascular complications encompass a broad spectrum of diseases that involve the myocardium, pericardium, coronary arteries, valves, and systemic and pulmonary vasculature. Traditional risk stratification tools do not accurately predict cardiovascular risk in this population. Multimodality imaging plays an essential role in the evaluation of various HIV-related cardiovascular complications. Here, we emphasize the role of multimodality imaging in establishing the diagnosis and aetiopathogenesis of various cardiovascular manifestations related to chronic HIV disease. This review also provides a critical appraisal of contemporary data and illustrative cases.
人类免疫缺陷病毒（HIV）感染是全球死亡和发病的主要原因。抗逆转录病毒疗法（ART）的引入显著降低了获得性免疫缺陷综合征的风险，并延长了预期寿命，接近普通人群。然而，尽管使用 ART 长期抑制病毒，HIV 感染者患心血管疾病的风险仍然大大增加。HIV 相关心血管并发症包括涉及心肌、心包、冠状动脉、瓣膜以及全身和肺血管的广泛疾病。传统的风险分层工具不能准确预测该人群的心血管风险。多模态成像在评估各种与 HIV 相关的心血管并发症中起着至关重要的作用。在这里，我们强调了多模态成像在确定与慢性 HIV 疾病相关的各种心血管表现的诊断和发病机制中的作用。本综述还对当代数据和说明性病例进行了批判性评估。
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