Department of Medical Chemistry and Laboratory Medicine, Poznan University of Medical Sciences, 61-701 Poznan, Poland.
Institute of Computing Science, Poznan University of Technology, 60-965 Poznan, Poland.
Int J Environ Res Public Health. 2023 Jan 27;20(3):2237. doi: 10.3390/ijerph20032237.
Guidelines for cardiovascular (CV) risk assessment among young adults are uncertain. Researchers are still looking for new tools for earlier diagnosis of cardiovascular diseases (CVD), the leading cause of mortality in the modern world. This study aimed to assess whether CV risk estimation is possible in groups of healthy individuals under the age of 40 on different dietary patterns (vegans-VEGAN ( = 48), lacto-/ovo-vegetarians-VEGE ( = 49), pescatarians-PESCA ( = 23), and omnivores-OMN ( = 35)) during the pandemic period. Four metrics containing selected risk classifiers were created, and participants were assessed using them. Groups including meat consumption showed increased CV risk predictions in the metrics assessment. The next analyzes showed statistically significant relationships between the results from the created metrics and selected non-basic biomarkers for ApoA1 (OMN group, = 0.028), IL-6 (PESCA group, = 0.048), HCY (VEGAN group, = 0.05), and hsCRP (OMN + PESCA groups, = 0.025). We found that predicting CV risk among healthy people under 40 adhering to different dietary patterns, taking into account basic and non-basic laboratory assessments and created metrics, is challenging but feasible. Furthermore, the OMN group appeared to be at the highest risk of increased CV risk in the future, while risk tended to be the lowest in the VEGAN group.
年轻人心血管 (CV) 风险评估指南尚不确定。研究人员仍在寻找新的工具,以便更早地诊断心血管疾病 (CVD),这是现代世界主要的死亡原因。本研究旨在评估在大流行期间,不同饮食模式(纯素食者-VEGAN(=48)、乳蛋素食者-VEGE(=49)、食鱼素食者-PESCA(=23)和杂食者-OMN(=35))下,40 岁以下健康人群的 CV 风险评估是否可行。创建了包含选定风险分类器的四个指标,并使用它们对参与者进行评估。包含肉类消费的组在指标评估中显示出增加的 CV 风险预测。接下来的分析表明,创建的指标结果与选定的非基本载脂蛋白 A1(OMN 组,=0.028)、IL-6(PESCA 组,=0.048)、HCY(VEGAN 组,=0.05)和 hsCRP(OMN + PESCA 组,=0.025)等非基本生物标志物之间存在统计学显著关系。我们发现,预测 40 岁以下遵循不同饮食模式的健康人群的 CV 风险具有挑战性但可行,同时考虑到基本和非基本实验室评估以及创建的指标。此外,OMN 组似乎未来发生增加 CV 风险的风险最高,而 VEGAN 组的风险则倾向于最低。