Nephrology and Haemodialysis Division, Internal Medicine Department, University Hospital of Split, 21000 Split, Croatia.
Department of Internal Medicine, School of Medicine, University of Split, 21000 Split, Croatia.
Int J Environ Res Public Health. 2023 Jan 27;20(3):2285. doi: 10.3390/ijerph20032285.
The aim of this study was to investigate the determinants of depression and nutritional status and their associations in patients treated with hemodialysis (HD) and peritoneal dialysis (PD) and the differences according to the type of treatment. There were fifty-three patients treated with maintenance HD and twenty patients treated with PD enrolled in this cross-sectional study. Body composition, anthropometric parameters, and clinical and laboratory parameters were collected for each participant. Depression was assessed with the Beck Depression Inventory II (BDI-II) and risk of malnutrition with the Malnutrition Inflammation Score (MIS). The results suggest a positive association between the level of depression and the percentage of fat mass and obesity parameters in PD and HD participants. Muscle mass and fat-free mass in HD, phase angle (PhA), and serum albumin levels in PD were negatively associated with the value of BDI-II. Participants treated with HD were found to have higher levels of pessimism and loss of interest in sex compared with PD. There is a need to integrate multidisciplinary psychological and nutritional assessment into the usual care of dialysis patients.
本研究旨在探讨接受血液透析 (HD) 和腹膜透析 (PD) 治疗的患者抑郁和营养状况的决定因素及其相关性,并根据治疗方式的不同进行比较。本横断面研究纳入了 53 名接受维持性 HD 治疗的患者和 20 名接受 PD 治疗的患者。为每位参与者收集了身体成分、人体测量参数以及临床和实验室参数。使用贝克抑郁量表 II(BDI-II)评估抑郁程度,使用营养不良炎症评分(MIS)评估营养不良风险。结果表明,PD 和 HD 参与者的抑郁程度与体脂肪百分比和肥胖参数呈正相关。HD 患者的肌肉量和去脂体重、PD 患者的相位角(PhA)和血清白蛋白水平与 BDI-II 值呈负相关。与 PD 相比,HD 治疗的参与者表现出更高的悲观情绪和性兴趣丧失。有必要将多学科心理和营养评估纳入透析患者的常规治疗中。