Department of Petrochemical Technology, Bharathidasan Institute of Technology Campus, University College of Engineering, Anna University, Tiruchirappalli 620 024, Tamil Nadu, India.
Department of Physics, National Institute of Technology (NIT), Tiruchirappalli 620 015, Tamil Nadu, India.
Int J Mol Sci. 2023 Jan 18;24(3):1947. doi: 10.3390/ijms24031947.
Multidrug-resistant strains (MDRs) are becoming a major concern in a variety of settings, including water treatment and the medical industry. Well-dispersed catalysts such as BiPO, ZnO nanoparticles (NPs), and different ratios of BiPO/ZnO nanocomposites (NCs) were synthesized through hydrothermal treatments. The morphological behavior of the prepared catalysts was characterized using XRD, Raman spectra, PL, UV-Vis diffuse reflectance spectroscopy (UV-DRS), SEM, EDX, and Fe-SEM. MDRs were isolated and identified by the 16s rDNA technique as belonging to , , , and . The antibacterial activity against MDRs and the photocatalytic methylene blue (MB) dye degradation activity of the synthesized NPs and NCs were studied. The results demonstrate that the prepared BiPO/ZnO-NCs (B1Z4-75:300; NCs-4) caused a maximum growth inhibition of 20 mm against and a minimum growth inhibition of 12 mm against at 80 μg mL concentrations of the NPs and NCs. Thus, NCs-4 might be a suitable alternative to further explore and develop as an antibacterial agent. The obtained results statistically justified the data ( ≤ 0.05) via one-way analysis of variance (ANOVA). According to the results of the antibacterial and photocatalytic study, we selected the best bimetallic NCs-4 for the photoexcited antibacterial effect of MDRs, including Gram ve and Gram ve strains, via UV light irradiation. The flower-like NCs-4 composites showed more effectiveness than those of BiPO, ZnO, and other ratios of NCs. The results encourage the development of flower-like NCs-4 to enhance the photocatalytic antibacterial technique for water purification.
多药耐药菌株（MDRs）在各种环境中，包括水处理和医疗行业，正成为一个主要关注点。通过水热处理合成了分散良好的催化剂，如 BiPO、ZnO 纳米粒子（NPs）和不同比例的 BiPO/ZnO 纳米复合材料（NCs）。使用 XRD、拉曼光谱、PL、UV-Vis 漫反射光谱（UV-DRS）、SEM、EDX 和 Fe-SEM 对制备的催化剂的形态行为进行了表征。通过 16s rDNA 技术分离并鉴定了多药耐药菌株，它们属于 、 、 和 。研究了合成的 NPs 和 NCs 对 MDRs 的抗菌活性和光催化亚甲基蓝（MB）染料降解活性。结果表明，制备的 BiPO/ZnO-NCs（B1Z4-75:300；NCs-4）在 NPs 和 NCs 的 80 μg mL 浓度下，对 和 分别产生了最大 20 mm 的生长抑制和最小 12 mm 的生长抑制。因此，NCs-4 可能是一种合适的替代品，可以进一步探索和开发作为抗菌剂。通过单因素方差分析（ANOVA）对获得的数据进行了统计学验证（ ≤ 0.05）。根据抗菌和光催化研究的结果，我们选择了最好的双金属 NCs-4 用于光激发对 MDRs 的抗菌作用，包括革兰氏阳性和革兰氏阴性菌株，通过紫外光照射。花状 NCs-4 复合材料比 BiPO、ZnO 和其他比例的 NCs 更有效。这些结果鼓励开发花状 NCs-4，以增强用于水净化的光催化抗菌技术。
