Subramanian Harinee, Krishnan Muthukumar, Mahalingam Ashok
Department of Physics, National Institute of Technology (NIT) Tiruchirappalli - 620 015 Tamil Nadu India
RSC Adv. 2022 Jan 5;12(2):985-997. doi: 10.1039/d1ra08196a. eCollection 2021 Dec 22.
Drug-resistant superbugs (DRS) were isolated from hospital sewage waste and confirmed by a 16S rDNA molecular technique as , , , and . Green nanotechnologies provide a new promising alternative pathway that was found to be much safer, eco-friendly, and has economic benefits over physical/chemical methods. (SM) mediated zinc oxide nanoparticles (ZnO-NPs) were proved to be photocatalytic and anti-microbial agents. Anti-microbial action was demonstrated by a maximal growth inhibition activity of 18 mm against and a minimal of 12 mm against at 80 μg mL concentrations. The anti-microbial mechanism of SMZnO-NPs employed a biphasic phenomenon persuaded by an osmotic shock that can attack the DRS bacterial cells directly and lead to death. In addition, photocatalytic activity was investigated by SMZnO-NPs for the degradation of methylene blue (MB) dye under different light conditions. Natural sunlight irradiation shows effective enhancement with the highest efficiencies of 96% being achieved within 60 min compared to UV-light and visible-light. The reusability of SMZnO-NPs provides up to 6 consecutive cycles towards MB decolorization for environmental water cleansing.
从医院污水废物中分离出耐药超级细菌（DRS），并通过16S rDNA分子技术确认为 、 、 和 。绿色纳米技术提供了一条新的有前景的替代途径，发现它比物理/化学方法更安全、环保且具有经济效益。 （SM）介导的氧化锌纳米颗粒（ZnO-NPs）被证明是光催化和抗菌剂。在80μg/mL浓度下，对 的最大生长抑制活性为18mm，对 的最小生长抑制活性为12mm，证明了其抗菌作用。SMZnO-NPs的抗菌机制采用了一种由渗透休克诱导的双相现象，这种现象可以直接攻击DRS细菌细胞并导致其死亡。此外，研究了SMZnO-NPs在不同光照条件下对亚甲基蓝（MB）染料的光催化降解活性。与紫外光和可见光相比，自然阳光照射显示出有效的增强作用，在60分钟内最高效率可达96%。SMZnO-NPs的可重复使用性为环境水净化提供了多达6个连续的MB脱色循环。
