Department of Biocosmetics, Sungkyunkwan University, Suwon 16419, Republic of Korea.
School of Systems Biomedical Science, Soongsil University, Seoul 06978, Republic of Korea.
Int J Mol Sci. 2023 Jan 21;24(3):2136. doi: 10.3390/ijms24032136.
Flavonoids have been shown to have anti-oxidative effects, as well as other health benefits (e.g., anti-inflammatory and anti-tumor functions). Luteolin (3', 4', 5,7-tetrahydroxyflavone) is a flavonoid found in vegetables, fruits, flowers, and herbs, including celery, broccoli, green pepper, navel oranges, dandelion, peppermint, and rosemary. Luteolin has multiple useful effects, especially in regulating inflammation-related symptoms and diseases. In this paper, we summarize the studies about the immunopharmacological activity of luteolin on anti-inflammatory, anti-cardiovascular, anti-cancerous, and anti-neurodegenerative diseases published since 2018 and available in PubMed or Google Scholar. In this review, we also introduce some additional formulations of luteolin to improve its solubility and bioavailability.
类黄酮具有抗氧化作用以及其他健康益处（例如，抗炎和抗肿瘤功能）。木樨草素（3'，4'，5，7-四羟基黄酮）是一种存在于蔬菜、水果、花卉和草药中的类黄酮，包括芹菜、西兰花、青椒、脐橙、蒲公英、薄荷和迷迭香。木樨草素具有多种有益作用，特别是在调节与炎症相关的症状和疾病方面。在本文中，我们总结了自 2018 年以来在 PubMed 或 Google Scholar 上发表的关于木樨草素在抗炎、心血管保护、抗癌和神经退行性疾病方面的免疫药理学活性的研究。在这篇综述中，我们还介绍了一些木樨草素的其他配方，以提高其溶解度和生物利用度。
