Eichenlaub D, Reimann E, Bunjes R
Dtsch Med Wochenschr. 1979 Feb 23;104(8):288-92. doi: 10.1055/s-0028-1103896.
Since 1974 an epidemic of tertian malaria has been spreading around the Adana and Tarsus townships in southern Turkey, with a peak incidence of 115 500 cases in 1977. A further increase is to be expected because the insect vectors have become resistant to insecticides. Since 1975 eleven children and three adults have been treated for P. vivax malaria. They had all stayed in the epidemic area during the transmission season which lasts from July to October. Because of a long primary latent period seven patients only developed first manifestations of the disease six to nine months after leaving Turkey. The classical malarial paroxysms were missing during the first weeks of the primary attack. Several children had a febrile illness over weeks with headache, vomiting, abdominal pain, hepatosplenomegaly, high blood-sedimentation rate and severe haemolytic anaemia, so that appendicitis or septicaemia had been suspected. Tetracyclines and trimethroprimsulphamethoxazole were able to suppress the disease without preventing relapses.
自1974年以来，间日疟在土耳其南部的阿达纳和塔尔苏斯镇周围流行，1977年发病率达到峰值，为115500例。由于病媒昆虫已对杀虫剂产生抗药性，预计发病率还会进一步上升。自1975年以来，已有11名儿童和3名成人接受了间日疟的治疗。他们在7月至10月的传播季节都曾在疫区停留。由于初次潜伏期较长，7名患者在离开土耳其6至9个月后才首次出现该病症状。初次发作的最初几周没有典型的疟疾发作。几名儿童数周来持续发热，伴有头痛、呕吐、腹痛、肝脾肿大、血沉加快和严重溶血性贫血，因此曾怀疑是阑尾炎或败血症。四环素和甲氧苄啶磺胺甲恶唑能够抑制该病，但无法预防复发。
