Suppr超能文献

马尾区散发性血管母细胞瘤:一例报告并文献复习。

Sporadic hemangioblastoma of cauda equina: A case-report and brief literature review.

机构信息

Neurosurgical Unit of Miulli Hospital, Acquaviva delle Fonti, Italy.

Neurosurgical Unit of Miulli Hospital, Acquaviva delle Fonti, Italy.

出版信息

Neurocirugia (Astur : Engl Ed). 2023 May-Jun;34(3):153-158. doi: 10.1016/j.neucie.2022.11.019. Epub 2023 Feb 9.

Abstract

Hemangioblastomas are rare lesions accounting for 1-5% of all spinal cord tumors and are mostly associated with von Hippel-Lindau syndrome. Localization in the cauda equina is uncommon. In this manuscript we aim to describe a rare case of sporadic intradural extramedullary hemangioblastoma of the cauda equina and present a literature review. A systematic research was performed on Pubmed, MEDLINE, and Google Scholar, using as keywords "spinal hemangioblastoma" and "cauda equina tumors". The previous literature is integrated by the description of the present case. A 49 year-old female, presented on August 2020 to our institution suffering from claudication neurogena, right sciatica and paraesthesia in right L5 radicular dermatome for more than 3 months. Neurological examination revealed hypoesthesia on right L5 dermatome and weakness of right anterior tibialis muscle. An MRI which showed an intradural mass at L1/2 level and an angiography that showing a nidus of serpiginous vessels inside the lesion. Microsurgical en bloc resection of lesion was performed with adjuvant neurophisological intra operative monitorings. Histological examination provided the diagnosis of hemangioblastoma. After surgery symptoms and neurological impairment gradually improved. A 10 months post-operative MRI showed no residual tumor. Although intradural extramedullary hemangioblastoma of the cauda equina without von Hippel-Lindau syndrome it is a rare pathological entity, this diagnosis must be taken in for cauda equina masses. Preoperative embolization is an option to minimize intraoperative bleeding. Radiosurgery seems to prevent recurrences when the tumor is not completely excised. Complete surgical removal of the lesion is usually possible and lead to a low likelihood of recurrence.

摘要

血管母细胞瘤是一种罕见的病变,占所有脊髓肿瘤的 1-5%,主要与 von Hippel-Lindau 综合征相关。在马尾中定位不常见。在本文中,我们旨在描述一例罕见的散发性硬脊膜外马尾血管母细胞瘤病例,并进行文献复习。在 Pubmed、MEDLINE 和 Google Scholar 上进行了系统的研究,使用的关键词是“脊髓血管母细胞瘤”和“马尾肿瘤”。通过描述本病例,整合了以往的文献。一位 49 岁女性,于 2020 年 8 月因 3 个多月来的进行性神经源性跛行、右侧坐骨神经痛和右侧 L5 神经根皮节感觉异常来我院就诊。神经系统检查显示右侧 L5 皮节感觉减退和右侧胫骨前肌无力。MRI 显示 L1/2 水平硬脊膜内肿块,血管造影显示病变内有蛇形血管巢。通过使用术中神经生理监测的辅助进行肿瘤整块切除术。组织学检查提供了血管母细胞瘤的诊断。术后症状和神经功能障碍逐渐改善。术后 10 个月的 MRI 显示无残留肿瘤。虽然没有 von Hippel-Lindau 综合征的硬脊膜外马尾血管母细胞瘤是一种罕见的病理实体,但对于马尾肿块,必须考虑到这种诊断。术前栓塞是减少术中出血的一种选择。当肿瘤不能完全切除时,放射外科似乎可以预防复发。通常可以完全切除病变,且复发的可能性较低。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验