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约旦心力衰竭患者的血压控制及其相关因素。

Blood pressure control and its associated factors among patients with heart failure in Jordan.

机构信息

Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid, 22110, Jordan.

College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates.

出版信息

J Hum Hypertens. 2023 Nov;37(11):977-984. doi: 10.1038/s41371-023-00807-z. Epub 2023 Feb 11.

Abstract

Uncontrolled blood pressure (BP) has been associated with increased risk of cardiovascular events including heart failure. This study aimed to explore the factors associated with poor BP control among patients with heart failure at two major outpatient cardiology clinics in Jordan. Variables including socio-demographics, biomedical variables, in addition to disease and medication characteristics were collected using medical records and custom-designed questionnaire. The validated 4-item Medication Adherence Scale was used to assess medication adherence. Binary logistic regression analysis was conducted to explore the significant and independent predictors of poor BP control. Regression analysis results revealed that being not satisfied with the prescribed medication (OR = 2.882; 95% CI: 1.458-5.695; P < 0.01), reporting moderate medication adherence (OR = 0.203; 95% CI: 22 0.048-0.863; P < 0.05), not receiving digoxin (OR = 3.423; 95% CI: 1.346-8.707; P < 0.05), and not receiving aldosterone antagonist (OR = 2.044; 95% CI: 1.038-4.025; P < 0.05) were associated with poor BP control. Future interventions should focus on increasing medication satisfaction and enhancing medication adherence, in order to improve BP control among patients with heart failure.

摘要

血压控制不佳与心血管事件风险增加有关,包括心力衰竭。本研究旨在探讨约旦两家主要心内科门诊心力衰竭患者血压控制不佳的相关因素。使用病历和定制问卷收集了包括社会人口统计学、生物医学变量以及疾病和药物特征在内的变量。使用经过验证的 4 项药物依从性量表评估药物依从性。采用二元逻辑回归分析探讨血压控制不佳的显著和独立预测因素。回归分析结果表明,对所开药物不满意(OR=2.882;95%CI:1.458-5.695;P<0.01)、报告中等药物依从性(OR=0.203;95%CI:0.048-0.863;P<0.05)、未接受地高辛(OR=3.423;95%CI:1.346-8.707;P<0.05)和未接受醛固酮拮抗剂(OR=2.044;95%CI:1.038-4.025;P<0.05)与血压控制不佳相关。未来的干预措施应重点提高药物满意度和增强药物依从性,以改善心力衰竭患者的血压控制。

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