• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

与食用红曲米相关的横纹肌溶解症。

Rhabdomyolysis Related to Red Yeast Rice Ingestion.

作者信息

Santos Sara, Gomes Sara, Carvalho Inês, Bonito Inês, Carmo Célia

机构信息

Internal Medicine, Centro Hospitalar Barreiro-Montijo, Barreiro, PRT.

出版信息

Cureus. 2023 Jan 9;15(1):e33532. doi: 10.7759/cureus.33532. eCollection 2023 Jan.

DOI:10.7759/cureus.33532
PMID:36779111
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9906798/
Abstract

Red yeast rice is made by fermenting white rice with the fungus . It has lipid-lowering effects due to the presence of monacolin, produced by the fungus, and therefore shares the same biological and side effects as a statin, namely it may cause rhabdomyolysis. In this clinical case study, we report the case of a 50-year-old woman suffering from a sudden onset of chest discomfort and generalized myalgia. Laboratory findings were consistent with the diagnosis of rhabdomyolysis. The patient had been recently diagnosed with dyslipidemia in primary care, and decided to start eating red yeast rice, without informing clinicians. Clinical improvement was rapidly noticed after hydration, and blood sample results returned to normal. Awareness should be raised for the regulation of these products, as their consumption is rising, and patients are unaware of their potential side effects.

摘要

红曲米是通过白米与真菌发酵制成的。由于真菌产生的莫纳可林,它具有降血脂作用,因此与他汀类药物具有相同的生物学特性和副作用,即可能导致横纹肌溶解。在本临床病例研究中,我们报告了一名50岁女性突发胸部不适和全身肌痛的病例。实验室检查结果与横纹肌溶解的诊断一致。该患者最近在初级保健中被诊断为血脂异常,并决定开始食用红曲米,且未告知临床医生。补液后病情迅速改善,血液样本结果恢复正常。应提高对这些产品监管的认识,因为它们的消费量在上升,而患者并未意识到其潜在的副作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9906798/5025e6b27082/cureus-0015-00000033532-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9906798/fe1bfc907ebe/cureus-0015-00000033532-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9906798/5025e6b27082/cureus-0015-00000033532-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9906798/fe1bfc907ebe/cureus-0015-00000033532-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ca8/9906798/5025e6b27082/cureus-0015-00000033532-i02.jpg

相似文献

1
Rhabdomyolysis Related to Red Yeast Rice Ingestion.与食用红曲米相关的横纹肌溶解症。
Cureus. 2023 Jan 9;15(1):e33532. doi: 10.7759/cureus.33532. eCollection 2023 Jan.
2
Rhabdomyolysis due to red yeast rice (Monascus purpureus) in a renal transplant recipient.肾移植受者因红曲米(紫红曲霉)导致横纹肌溶解症。
Transplantation. 2002 Oct 27;74(8):1200-1. doi: 10.1097/00007890-200210270-00028.
3
Red Yeast Rice Preparations: Are They Suitable Substitutions for Statins?红曲制剂:可否替代他汀类药物?
Am J Med. 2017 Oct;130(10):1148-1150. doi: 10.1016/j.amjmed.2017.05.013. Epub 2017 Jun 7.
4
Stable isotope ratio analysis for authentication of red yeast rice.稳定同位素比分析用于鉴定红曲米。
Talanta. 2017 Nov 1;174:228-233. doi: 10.1016/j.talanta.2017.05.057. Epub 2017 May 23.
5
The effect of red yeast rice (Monascus purpureus) in dyslipidemia and other disorders.红曲(Monascus purpureus)在血脂异常及其他疾病中的作用。
Complement Ther Med. 2012 Dec;20(6):466-74. doi: 10.1016/j.ctim.2012.07.004. Epub 2012 Aug 17.
6
Safety and efficacy of red yeast rice (Monascus purpureus) as an alternative therapy for hyperlipidemia.红曲米(紫红曲霉)作为高脂血症替代疗法的安全性和有效性。
P T. 2009 Jun;34(6):313-27.
7
Red yeast rice for the treatment of dyslipidemia.红曲米用于治疗血脂异常。
Curr Atheroscler Rep. 2015 Apr;17(4):495. doi: 10.1007/s11883-015-0495-8.
8
Monascus purpureus for statin and ezetimibe intolerant heterozygous familial hypercholesterolaemia patients: A clinical study.红曲霉菌用于他汀类药物和依折麦布不耐受的杂合子家族性高胆固醇血症患者:一项临床研究。
Atheroscler Suppl. 2017 Nov;30:86-91. doi: 10.1016/j.atherosclerosissup.2017.05.021.
9
Functional food red yeast rice (RYR) for metabolic syndrome amelioration: a review on pros and cons.用于改善代谢综合征的功能性食品红曲米:利弊综述
World J Microbiol Biotechnol. 2016 May;32(5):87. doi: 10.1007/s11274-016-2035-2. Epub 2016 Apr 2.
10
A validated stability-indicating HPLC with photodiode array detector (PDA) method for the stress tests of Monascus purpureus-fermented rice, red yeast rice.一种经验证的采用光电二极管阵列检测器(PDA)的高效液相色谱法,用于红曲米(紫曲霉发酵米)的强制降解试验。
J Pharm Biomed Anal. 2005 Sep 1;39(1-2):82-90. doi: 10.1016/j.jpba.2005.03.005.

引用本文的文献

1
Red yeast rice with monacolin K for the improvement of hyperlipidemia: A narrative review.含莫纳可林K的红曲米改善高脂血症:一项叙述性综述。
World J Clin Cases. 2025 Sep 26;13(27):105415. doi: 10.12998/wjcc.v13.i27.105415.
2
Fulminant Red Yeast Rice-Associated Rhabdomyolysis with Acute Liver Injury and Hyperkalemia Treated with Extracorporeal Blood Purification Using CytoSorb.应用CytoSorb进行体外血液净化治疗暴发性红曲米相关横纹肌溶解症伴急性肝损伤和高钾血症
Drug Healthc Patient Saf. 2025 Apr 18;17:109-120. doi: 10.2147/DHPS.S519861. eCollection 2025.
3
Scientific Opinion on additional scientific data related to the safety of monacolins from red yeast rice submitted pursuant to Article 8(4) of Regulation (EC) No 1925/2006.

本文引用的文献

1
[Red yeast rice as the presumed cause of acute kidney and liver failure].[红曲米被认为是急性肾肝衰竭的病因]
Ugeskr Laeger. 2019 Sep 30;181(40).
2
Vitamin D Serum Levels in Patients with Statin-Induced Musculoskeletal Pain.他汀类药物引起的肌肉骨骼疼痛患者的血清维生素 D 水平。
Dis Markers. 2019 Mar 25;2019:3549402. doi: 10.1155/2019/3549402. eCollection 2019.
3
Acute liver injury induced by red yeast rice supplement.红曲补充剂引起的急性肝损伤。
关于根据欧盟第1925/2006号法规第8(4)条提交的与红曲米中莫纳可林安全性相关的补充科学数据的科学意见。
EFSA J. 2025 Feb 28;23(2):e9276. doi: 10.2903/j.efsa.2025.9276. eCollection 2025 Feb.
4
Rhabdomyolysis or Severe Acute Hepatitis Associated with the Use of Red Yeast Rice Extracts: an Update from the Adverse Event Reporting Systems.红曲米提取物相关横纹肌溶解症或严重急性肝炎:不良事件报告系统的最新情况。
Curr Atheroscler Rep. 2023 Nov;25(11):879-888. doi: 10.1007/s11883-023-01157-4. Epub 2023 Oct 13.
BMJ Case Rep. 2019 Mar 25;12(3):e227961. doi: 10.1136/bcr-2018-227961.
4
Variability in strength of red yeast rice supplements purchased from mainstream retailers.主流零售商购买的红曲米补充剂的强度差异。
Eur J Prev Cardiol. 2017 Sep;24(13):1431-1434. doi: 10.1177/2047487317715714. Epub 2017 Jun 23.
5
Improving health outcomes through patient education and partnerships with patients.通过患者教育以及与患者建立伙伴关系来改善健康状况。
Proc (Bayl Univ Med Cent). 2017 Jan;30(1):112-113. doi: 10.1080/08998280.2017.11929552.
6
Adverse reactions to dietary supplements containing red yeast rice: assessment of cases from the Italian surveillance system.含红曲米膳食补充剂的不良反应:来自意大利监测系统的病例评估
Br J Clin Pharmacol. 2017 Apr;83(4):894-908. doi: 10.1111/bcp.13171. Epub 2017 Jan 19.
7
Statin-induced rhabdomyolysis: a comprehensive review of case reports.他汀类药物引起的横纹肌溶解症:病例报告综述
Physiother Can. 2014 Spring;66(2):124-32. doi: 10.3138/ptc.2012-65.
8
The growing use of herbal medicines: issues relating to adverse reactions and challenges in monitoring safety.草药使用的日益增加:与不良反应相关的问题及安全性监测面临的挑战。
Front Pharmacol. 2014 Jan 10;4:177. doi: 10.3389/fphar.2013.00177.
9
2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines.2013年美国心脏病学会/美国心脏协会成人降低动脉粥样硬化性心血管风险的血胆固醇治疗指南:美国心脏病学会/美国心脏协会实践指南工作组报告
J Am Coll Cardiol. 2014 Jul 1;63(25 Pt B):2889-934. doi: 10.1016/j.jacc.2013.11.002. Epub 2013 Nov 12.
10
Interaction between Red Yeast Rice and CYP450 Enzymes/P-Glycoprotein and Its Implication for the Clinical Pharmacokinetics of Lovastatin.红曲米与 CYP450 酶/P-糖蛋白的相互作用及其对洛伐他汀临床药代动力学的影响。
Evid Based Complement Alternat Med. 2012;2012:127043. doi: 10.1155/2012/127043. Epub 2012 Nov 14.