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1 型与 2 型糖尿病患者与非糖尿病患者白内障手术结局的比较。

Comparison of cataract surgery outcomes in patients with type 1 vs type 2 diabetes mellitus and patients without diabetes mellitus.

机构信息

From the Department of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado.

出版信息

J Cataract Refract Surg. 2023 Jun 1;49(6):608-613. doi: 10.1097/j.jcrs.0000000000001167.

Abstract

PURPOSE

To report outcomes of cataract surgery in type 1 diabetes mellitus (T1DM) compared with type 2 diabetes mellitus (T2DM) and patients without diabetes mellitus (DM).

SETTING

Academic tertiary referral university hospital eye center, Aurora, Colorado.

DESIGN

Retrospective chart review using the University of Colorado Cataract Outcomes Database for all cataract surgeries between 2014 and 2020.

METHODS

Demographics, ocular history, and postoperative outcomes were compared across groups using general linear and logistic regression modeling with estimating equations to account for some patients having 2 eyes included.

RESULTS

8117 patients and 13 383 eyes were included. Compared with T2DM eyes undergoing cataract surgery (n = 3115), T1DM eyes (n = 233) were more likely to have a history of diabetic retinopathy (DR) (60.5% vs 23.6%, P < .0001), of which proliferative DR was the most common (63.1% vs 42.4%, P < .0001). T1DM eyes were also more likely to have a history of retinal detachment (RD) (9.0% vs 2.9%, P < .0001) and prior vitrectomy surgery (12.9% vs 4.0%, P < .0001). Despite having similar preoperative corrected distance visual acuity (CDVA) as T2DM eyes (logMAR 0.52 vs 0.44, P = .092), T1DM eyes had worse CDVA after cataract surgery (logMAR 0.27 vs 0.15, P = .0003). In a multivariate analysis, a history of proliferative DR and prior RD were significant predictors of worse postoperative CDVA ( P < .0001) but type of DM was not ( P = .894).

CONCLUSIONS

T1DM eyes have worse visual outcomes after cataract surgery compared with T2DM eyes. Worse postoperative visual acuity was associated with worse preoperative DR and history of RD rather than type of DM.

摘要

目的

报告与 2 型糖尿病(T2DM)和无糖尿病(DM)患者相比,1 型糖尿病(T1DM)患者白内障手术的结果。

背景

科罗拉多大学白内障手术结果数据库,科罗拉多州奥罗拉市的学术三级转诊大学医院眼中心。

设计

对 2014 年至 2020 年间所有白内障手术的病历进行回顾性图表审查。

方法

使用一般线性和逻辑回归模型以及估算方程,比较各组之间的人口统计学、眼部病史和术后结果,以考虑一些患者有 2 只眼纳入。

结果

共纳入 8117 名患者和 13383 只眼。与接受白内障手术的 T2DM 眼(n=3115)相比,T1DM 眼(n=233)更有可能有糖尿病视网膜病变(DR)病史(60.5%比 23.6%,P<0.0001),其中增殖性 DR 最常见(63.1%比 42.4%,P<0.0001)。T1DM 眼也更有可能有视网膜脱离(RD)病史(9.0%比 2.9%,P<0.0001)和既往玻璃体切除术(12.9%比 4.0%,P<0.0001)。尽管 T1DM 眼的术前矫正远视力(CDVA)与 T2DM 眼相似(logMAR 0.52 比 0.44,P=0.092),但白内障手术后 T1DM 眼的 CDVA 更差(logMAR 0.27 比 0.15,P=0.0003)。在多变量分析中,增殖性 DR 和既往 RD 史是术后 CDVA 差的显著预测因素(P<0.0001),但 DM 类型不是(P=0.894)。

结论

与 T2DM 眼相比,T1DM 眼白内障手术后视力结果更差。术后视力较差与术前 DR 较差和 RD 病史相关,而与 DM 类型无关。

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