Pediatr Ann. 2023 Feb;52(2):e57-e61. doi: 10.3928/19382359-20230102-05. Epub 2023 Feb 1.
Genetic abnormalities are responsible for up to 70% of severe, early onset obesity. With recent advances in genetic testing, more individuals with genetic etiology of excessive weight are being identified. However, treatment will need to be individualized based on the cause and underlying pathophysiology. Several treatment options are being investigated, and there are several treatment options now commercially available for some of these genetic conditions. .
遗传异常导致高达 70%的严重早发性肥胖。随着基因检测技术的进步，越来越多具有超重遗传病因的个体被发现。然而，治疗需要根据病因和潜在病理生理学进行个体化。目前正在研究几种治疗选择，并且对于其中一些遗传疾病，现在已经有几种商业上可用的治疗选择。
