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嗜冷栖热菌,一种新出现的人类病原体:来自一家葡萄牙医院的4例病例系列

Shewanella algae, an Emerging Human Pathogen: A Series of Four Cases From a Portuguese Hospital.

作者信息

Fernandes Salomão, Sérvio Rita, Silva Ana Rita, Tavares Raquel, Rodrigues Paulo

机构信息

Infectious Diseases, Hospital Beatriz Ângelo, Loures, PRT.

出版信息

Cureus. 2023 Jan 12;15(1):e33686. doi: 10.7759/cureus.33686. eCollection 2023 Jan.

Abstract

is a rod-shaped, Gram-negative bacterium that is considered an emerging human pathogen. Traditionally associated with warmer climates, has now been isolated from patients worldwide, and reports of infection are increasing. In a regional hospital on the outskirts of Lisbon, Portugal, four cases have been detected in the past 10 years. Two of the patients were migrants from African countries with daily contact with water; the other two patients were Portuguese, and no epidemiological risk factors were found among them. These are the first cases reported in Portugal. Risk factors associated with in patients discussed in this paper include the following: human immunodeficiency virus (HIV) infection, chronic venous insufficiency, lower limb ulcers, chronic kidney disease, diabetes, arterial hypertension, dilated cardiomyopathy, atrial fibrillation, chronic hepatic disease, and chronic pancreatitis. One patient died in the intensive care unit with septic shock and disseminated intravascular coagulation from a fulminant infection secondary to bacteraemia. The four clinical cases presented in this case series highlight the clinical features of this infection so that other physicians can successfully identify and treat infections.

摘要

是一种杆状革兰氏阴性菌,被认为是一种新兴的人类病原体。传统上与温暖气候相关,现在已在世界各地的患者中分离出来,且感染报告不断增加。在葡萄牙里斯本郊区的一家地区医院,过去10年中检测到4例病例。其中两名患者是来自非洲国家的移民,每天与水接触;另外两名患者是葡萄牙人,未发现他们有流行病学危险因素。这些是葡萄牙报告的首例病例。本文讨论的患者中与该菌相关的危险因素包括:人类免疫缺陷病毒(HIV)感染、慢性静脉功能不全、下肢溃疡、慢性肾病、糖尿病、动脉高血压、扩张型心肌病、心房颤动、慢性肝病和慢性胰腺炎。一名患者在重症监护病房因继发于该菌败血症的暴发性感染导致感染性休克和弥散性血管内凝血而死亡。本病例系列中呈现的4例临床病例突出了这种感染的临床特征,以便其他医生能够成功识别和治疗该菌感染。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/86a0/9920493/2fce9be68952/cureus-0015-00000033686-i01.jpg

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