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以意识改变为表现的黏液性水肿昏迷患者的惊人诊断

Surprising Diagnosis of Myxedema Crisis In-Patient Who Presented With Altered Sensorium.

作者信息

Umalkar Gajanan N, Chavan Gajanan, Gadkari Charuta, Wanjari Mayur B

机构信息

Emergency Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.

Research and Development, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.

出版信息

Cureus. 2023 Jan 13;15(1):e33743. doi: 10.7759/cureus.33743. eCollection 2023 Jan.

Abstract

Hypothyroidism, a disorder of decreased thyroid hormone secretion diagnosed by increased thyroid stimulating hormone (TSH) and low free triiodothyronine (FT3) and free thyroxine (FT4) levels, is classified as primary and secondary hypothyroidism, depending on the pathology. Raised TSH levels are associated with primary hypothyroidism, while decreased levels of TSH are seen in secondary hypothyroidism. With the easy availability of diagnostic tests, hypothyroidism can be detected and managed early but can be life-threatening if not treated within time. Manifestations of hypothyroidism are dry skin, hoarseness of voice, weight gain, constipation, cold intolerance, fatigue, and lethargy; however, the clinical presentation can differ as per age and sex and person to person. Here, we present one such case, which was brought to the emergency room with a history of altered sensorium, hypotension, and swelling over the bilateral lower limbs and face, with a surprise diagnosis of myxedema crisis. The uniqueness of this case is the omnipresent availability of early diagnosis and treatment in this era. still got a female patient with altered sensorium who was diagnosed to be a myxedema crisis which was given a lesser thought in our provisional diagnosis.

摘要

甲状腺功能减退症是一种甲状腺激素分泌减少的疾病,通过促甲状腺激素(TSH)升高以及游离三碘甲状腺原氨酸(FT3)和游离甲状腺素(FT4)水平降低来诊断,根据病理情况可分为原发性和继发性甲状腺功能减退症。TSH水平升高与原发性甲状腺功能减退症相关,而TSH水平降低则见于继发性甲状腺功能减退症。随着诊断测试的容易获得,甲状腺功能减退症可以早期被检测和管理,但如果不及时治疗可能会危及生命。甲状腺功能减退症的表现包括皮肤干燥、声音嘶哑、体重增加、便秘、不耐寒、疲劳和嗜睡;然而,临床表现可能因年龄、性别和个体差异而有所不同。在此,我们呈现这样一个病例,该患者因意识改变、低血压以及双侧下肢和面部肿胀的病史被送往急诊室,最终令人惊讶地诊断为黏液性水肿昏迷。该病例的独特之处在于在这个时代早期诊断和治疗普遍可得的情况下,我们最初对一名意识改变的女性患者诊断为黏液性水肿昏迷的考虑较少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e062/9922525/7f33d6fc9452/cureus-0015-00000033743-i01.jpg

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