Tatsuta M, Iishi H, Okuda S
Department of Gastrointestinal Oncology, Center for Adult Diseases, Osaka.
Hepatogastroenterology. 1987 Oct;34(5):223-8.
The effects of cigarette smoking on the location, healing and recurrence of gastric ulcers were investigated by endoscopy. The endoscopic Congo red test developed in this clinic revealed a close relationship between the location of gastric ulcers and the extent of the acid-secreting area, and the smoking index. In general, in patients with a high smoking index, gastric ulcers were located proximally and the acid-secreting area was small. These findings indicate that smoking is associated with the development of fundal gastritis and also with the development of high-lying ulcers. Healing of gastric ulcers was significantly faster, and their recurrence was significantly less frequent in patients who stopped smoking or reduced smoking by a half or more after treatment, than in those who did not.
