Tatsuta M, Okuda S
Gastroenterology. 1976 Jul;71(1):16-8.
Gastric ulcers have been thought to occur only in the pyloric gland area. However, endoscopic examinations using the Congo red test showed that 18 of the ulcers examined (7.8%) were surrounded by an acid-secreting area, and so were in the fundic gland area. Histological examination of specimens obtained by gastrectomy also showed that five of the lesions examined (4.5%) were located in the fundic gland area. Ulcers in the fundic gland area were found most frequently in the angle and lower gastric body, adjacent to acid-secreting boundary. These ulcers were associated with little or no fundal gastritis, whereas ulcers in the pyloric gland area were usually associated with moderate or severe fundal gastritis. Unlike ulcers of similar depth in the pyloric gland area, ulcers surrounded by normal fundic mucosa healed rapidly and completely. No recurrence of these ulcers was seen in a 1-year endoscopic follow-up period.
胃溃疡一直被认为仅发生在幽门腺区域。然而，使用刚果红试验的内镜检查显示，所检查的溃疡中有18例（7.8%）被泌酸区域包围，因此位于胃底腺区域。胃切除术获得的标本的组织学检查也显示，所检查的病变中有5例（4.5%）位于胃底腺区域。胃底腺区域的溃疡最常见于角部和胃体下部，靠近泌酸边界。这些溃疡很少或几乎没有伴有胃底胃炎，而幽门腺区域的溃疡通常伴有中度或重度胃底胃炎。与幽门腺区域深度相似的溃疡不同，被正常胃底黏膜包围的溃疡愈合迅速且完全。在1年的内镜随访期内未见这些溃疡复发。
